Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation [PDF]
Frontiers in Immunology, 2018 Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work in concert with other pattern recognition receptors (PRRs).
Carlos del Fresno +5 more
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NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo [PDF]
Journal of Inflammation Research, 2020 Amir I Tukhvatulin, Alina S Dzharullaeva, Alina S Erokhova, Dmitry V Scheblyakov, Boris S Naroditsky, Alexander L Gintsburg, Denis Y Logunov N. F. Gamaleya National Research Center for Epidemiology and Microbiology, Moscow, RussiaCorrespondence: Amir I ...
Tukhvatulin AI +6 more
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Myeloid C-type lectin receptors in innate immune recognition
ImmunityC-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a remarkable ability to recognize an extensive array of ligands, from carbohydrates and beyond, and encompass pattern-associated molecular patterns (PAMPs), damage-associated ...
Caetano Reis e Sousa +2 more
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The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation
Frontiers in Immunology, 2021 More than fifty c-type lectin receptors (CLR) are known and have been identified so far. Moreover, we know the group of galectins and sialic acid-binding immunoglobulin-type lectins that also belong to the carbohydrate-binding receptors of the immune ...
Karin Peters, Marcus Peters
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Key thermally dimorphic fungal pathogens: shaping host immunity
Open Biology, 2022 Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft +2 more
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Information transfer in mammalian glycan-based communication
eLife, 2023 Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger +6 more
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C-type Lectin Receptors for Tumor Eradication: Future Directions [PDF]
Cancers, 2011 Dendritic cells are key regulators in directing immune responses and therefore are under extensive research for the induction of anti-tumor responses. DCs express a large array of receptors by which they scan their surroundings for recognition and uptake of pathogens.
Streng-Ouwehand, Ingeborg +2 more
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The diverse roles of C-type lectin-like receptors in immunity
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
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T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors.
Trends Immunol, 2020 Speakman EA +3 more
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Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. [PDF]
PLoS ONE, 2013 Mannose-binding lectin (MBL) is a key soluble effector of the innate immune system that recognizes pathogen-specific surface glycans. Surprisingly, low-producing MBL genetic variants that may predispose children and immunocompromised individuals to ...
Matthew Brudner +22 more
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