Results 101 to 110 of about 111,292 (192)

Circulating FGF21 is lower in South Asians compared with Europids with type 2 diabetes mellitus

Endocrine Connections
Objective: Inflammation contributes to the development of type 2 diabetes mellitus (T2DM). While South Asians are more prone to develop T2DM than Europids, the inflammatory phenotype of the South Asian population remains relatively unknown. Therefore, we
Carlijn A Hoekx, Borja Martinez-Tellez, Maaike E Straat, Maurice B Bizino, Huub J van Eyk, Hildebrandus J Lamb, Johannes W A Smit, Ingrid M Jazet, Kimberly J Nahon, Laura G M Janssen, Patrick C N Rensen, Mariëtte R Boon   +11 more
doaj   +1 more source

Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas. [PDF]

, 2019
PurposeGlioblastoma (GBM) remains an incurable disease despite extensive treatment with surgical resection, irradiation, and temozolomide. In line with many other forms of aggressive cancers, GBM is currently under consideration as a target for ...
Kaprealian, Tania, Lee, Mi-Heon, McBride, William H, Nesseler, Jean Philippe, Nickers, Philippe, Niclou, Simone P, Schaue, Dorthe   +6 more
core  

Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics

Journal of Integrative Neuroscience
Background: Thalamic hemorrhage pain (THP), a subtype of central post-stroke pain (CPSP), commonly develops following ischemic or hemorrhagic injury to the thalamus.
Chen Yang, Ju Gao, Yaqun Li, Yinggang Xiao, Tianfeng Huang   +4 more
doaj   +1 more source

Modulation of parietal cytokine and chemokine gene profiles by mesenchymal stem cell as a basis for neurotrauma recovery

Journal of the Formosan Medical Association, 2019
Background & purpose: Following traumatic brain injury (TBI), primary mechanical injury to the brain may cause blood-brain-barrier damage followed by secondary injury, ultimately culminating in cell death.
Cheng-Hsien Lin, Willie Lin, Yu-Chin Su, Yogi Cheng-Yo Hsuan, Yu-Chien Chen, Ching-Ping Chang, Willy Chou, Kao-Chang Lin   +7 more
doaj   +1 more source

The Role of CXCL12-CXCR4 Signaling Pathway in Pancreatic Development

Theranostics, 2013
Chemokine (C-X-C motif) receptor 4 (CXCR4) is the receptor for chemokine (C-X-C motif) ligand 12 (CXCL12, also known as stromal derived factor-1, Sdf1).
Keiichi Katsumoto, Shoen Kume
doaj  

Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis

Frontiers in Immunology
ObjectivePain is a prevalent discomfort symptom associated with cancer, yet the correlations and potential mechanisms between pain and the efficacy of cancer immunotherapy remain uncertain.MethodsNon-small cell lung cancer (NSCLC) patients who received ...
Zexin Zhang, Wenjie Zhao, Chang Lv, Zexia Wu, Wenhao Liu, Xuesong Chang, Xuesong Chang, Yaya Yu, Yaya Yu, Zhenzhen Xiao, Zhenzhen Xiao, Yihan He, Yihan He, Haibo Zhang, Haibo Zhang, Haibo Zhang, Haibo Zhang, Haibo Zhang   +17 more
doaj   +1 more source

The Role of Macrophage Dynamics in Atherosclerosis Analyzed Using a Petri Net-Based Model

Applied Sciences
Atherosclerosis, a chronic inflammatory and oxidative stress-mediated disease impacting the arterial system, stands as a primary cause of morbidity and mortality worldwide.
Agnieszka Rybarczyk, Dorota Formanowicz, Piotr Formanowicz   +2 more
doaj   +1 more source

Blood and sputum biomarkers in COPD and asthma: a review [PDF]

, 2016
Chronic obstructive pulmonary disease (COPD) and asthma are lung inflammatory diseases that represent major public health problems. The primary, and often unique, method to evaluate lung function is spirometry, which reflects disease severity rather than
Conti, V, De Marchis, L, Graziani, C, Ialleni, E, Leone, V, Munafò, G, Paone, G, Ramaccia, M, Salducci, M   +8 more
core  

Physical exercise promotes white matter repair after ischemic stroke

Neural Regeneration Research
White matter injury is a key factor impacting stroke recovery. Physical exercise can promote white matter repair. Immune cells, especially regulatory T (Treg) cells, contribute to strengthening white matter integrity, yet little is known about the ...
Yating Mu, Xiaofeng Yang, Yifeng Feng, Liying Zhang, Jinghui Xu, Mingyue Li, Rui Wu, Shiying Li, Xiaofei He, Zejie Zuo, Xiquan Hu   +10 more
doaj   +1 more source

Recent approaches of antibody therapeutics in androgenetic alopecia

Frontiers in Pharmacology
Therapeutic antibodies (Abs) have been anticipated as promising alternatives to conventional treatments such as topical minoxidil and oral finasteride for androgenetic alopecia (AGA).
Su-Eon Jin, Jino Kim, Jong-Hyuk Sung
doaj   +1 more source