Results 21 to 30 of about 92,407 (159)

CXCL12 (chemokine (C-X-C motif) ligand 12) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017
Review on CXCL12, with data on DNA, on the protein encoded, and where the gene is implicated.
Giulia Gentile, Maria Guarnaccia, Sebastiano Cavallaro   +2 more
openaire   +4 more sources

Chemokines in ICU Delirium: An Exploratory Study

Critical Care Explorations, 2022
OBJECTIVES:. The pathophysiology of delirium is complex and incompletely understood. Inflammation is hypothesized to be integral to its development due to effects on blood brain barrier integrity, facilitation of leukocyte extravasation into brain ...
Ryan J. Smith, MD, JD, Alejandro A. Rabinstein, MD, Rodrigo Cartin-Ceba, MD, MSc, Vijay P. Singh, MBBS, MD, Christian Lachner, MD, Biswajit Khatua, PhD, Shubham Trivedi, BS, Ognjen Gajic, MD   +7 more
doaj   +1 more source

Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study

Critical Care Explorations, 2022
OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD, Talita Souza-Siqueira, PhD, Eliane Borges da Silva, PhD, Laiane Cristina dos Santos de Oliveira, PhD, Rodrigo Cerqueira Borges, PhD, Heloísa H de Oliveira Alves, PhD, Laureane Nunes Masi, PhD, Gilson Masahiro Murata, PhD, Renata Gorjão, PhD, Adriana Cristina Levada-Pires, PhD, Antônio Carlos Nogueira, PhD, Tânia Cristina Pithon-Curi, PhD, Ricardo Bentes de Azevedo, PhD, Francisco Garcia Soriano, MD, PhD, Rui Curi, PhD, Marcel Cerqueira Cesar Machado, MD, PhD   +15 more
doaj   +1 more source

Potential of C‐X‐C motif chemokine ligand 1/8/10/12 as diagnostic and prognostic biomarkers in idiopathic pulmonary arterial hypertension [PDF]

The Clinical Respiratory Journal, 2021
AbstractObjectiveThis study aimed to evaluate the clinical role of C‐X‐C motif chemokine ligand (CXCL) family members in idiopathic pulmonary arterial hypertension (IPAH) patients.MethodsCXCL1, CXCL8, CXCL10 and CXCL12 expressions in the serum samples of IPAH patients (N = 39) and age‐/gender‐matched controls (N = 40) were detected by enzyme‐linked ...
Zhenhua Li, Jie Jiang, Shan Gao
openaire   +2 more sources

Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis

F&S Science, 2023
To study the effect of intrauterine injection of C-X-C motif chemokine ligand 12 (CXCL12), also known as a stem cell chemoattractant (stromal cell-derived factor 1), on fertility and endometrial receptivity in mice with endometriosis.Laboratory study.Academic Medical Center.Fifty-six mice underwent chemotherapy and bone marrow transplantation.
Ana Carolina Japur de Sá Rosa-e-Silva, Ramanaiah Mamillapalli, Julio Cesar Rosa-e-Silva, Abdullah Ucar, Joshua Schwartz, Hugh S. Taylor   +5 more
openaire   +2 more sources

Isolation and characterization of cancer-associated fibroblasts in the tumor microenvironment of hepatocellular carcinoma [PDF]

Journal of Liver Cancer, 2023
Background/Aim Cancer-associated fibroblasts (CAFs) play an immunosuppressive role in the tumor microenvironment (TME) of human cancers; however, their characteristics and role in hepatocellular carcinoma (HCC) remain to be elucidated. Methods Nine tumor
Kyoungdo Mun, Jiwon Han, Pureun Roh, Jonggeun Park, Gahee Kim, Wonhee Hur, Jeongwon Jang, Jongyoung Choi, Seungkew Yoon, Youngkyoung You, Hojoong Choi, Pilsoo Sung   +11 more
doaj   +1 more source

Immunological effects of anti-coagulant unfractionated heparin in pregnant Chinese women with cryptic recurrent miscarriages

Archives of Medical Science, 2020
Introduction Anti-coagulant unfractionated heparin of low molecular weight (ACUHlmw) therapy is popularly practised in the therapy of recurrent miscarriages (RMC) due to its anti-coagulant properties.
Yanli Hong, Ke Hong, Xiaojuan Chen, Jinting Xue, Yanyun Yin   +4 more
doaj   +1 more source

Temporal characteristics of astrocytic activation in the TNC in a mice model of pain induced by recurrent dural infusion of inflammatory soup

The Journal of Headache and Pain, 2022
Background Astrocytic activation might play a significant role in the central sensitization of chronic migraine (CM). However, the temporal characteristics of the astrocytic activation in the trigeminal nucleus caudalis (TNC) and the molecular mechanism ...
Leyi Zhang, Chenglong Lu, Li Kang, Yingji Li, Wenjing Tang, Dengfa Zhao, Shengyuan Yu, Ruozhuo Liu   +7 more
doaj   +1 more source

Stromal Cell-Derived Factor-1 (Chemokine C-X-C Motif Ligand 12) and Chemokine C-X-C Motif Receptor 4 Are Required for Migration of Gonadotropin-Releasing Hormone Neurons to the Forebrain [PDF]

Journal of Neuroscience, 2006
Gonadotropin-releasing hormone (GnRH) neurons migrate from the vomeronasal organ (VNO) in the nasal compartment to the basal forebrain in mice, beginning on embryonic day 11 (E11). These neurons use vomeronasal axons as guides to migrate through the nasal mesenchyme.
Schwarting, Gerald A., Henion, Timothy R., Nugent, J. David, Caplan, Benjamin, Tobet, Stuart A.   +4 more
openaire   +3 more sources

A new clinical prognostic nomogram for liver cancer based on immune score.

PLoS ONE, 2020
BackgroundIncreased attention is being paid to the relationship between the immune status of the tumor microenvironment and tumor prognosis. The application of immune scoring in evaluating the clinical prognosis of liver cancer patients has not yet been ...
Qinyan Shen, Guinv Hu, JinZhong Wu, Liting Lv   +3 more
doaj   +1 more source