Results 41 to 50 of about 55,700 (269)

Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study

Critical Care Explorations, 2022
OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD, Talita Souza-Siqueira, PhD, Eliane Borges da Silva, PhD, Laiane Cristina dos Santos de Oliveira, PhD, Rodrigo Cerqueira Borges, PhD, Heloísa H de Oliveira Alves, PhD, Laureane Nunes Masi, PhD, Gilson Masahiro Murata, PhD, Renata Gorjão, PhD, Adriana Cristina Levada-Pires, PhD, Antônio Carlos Nogueira, PhD, Tânia Cristina Pithon-Curi, PhD, Ricardo Bentes de Azevedo, PhD, Francisco Garcia Soriano, MD, PhD, Rui Curi, PhD, Marcel Cerqueira Cesar Machado, MD, PhD   +15 more
doaj   +1 more source

Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis

F&S Science, 2023
To study the effect of intrauterine injection of C-X-C motif chemokine ligand 12 (CXCL12), also known as a stem cell chemoattractant (stromal cell-derived factor 1), on fertility and endometrial receptivity in mice with endometriosis.Laboratory study.Academic Medical Center.Fifty-six mice underwent chemotherapy and bone marrow transplantation.
Ana Carolina Japur de Sá Rosa-e-Silva, Ramanaiah Mamillapalli, Julio Cesar Rosa-e-Silva, Abdullah Ucar, Joshua Schwartz, Hugh S. Taylor   +5 more
openaire   +2 more sources

Reciprocal crosstalk between endometrial carcinoma and mesenchymal stem cells via transforming growth factor-β/transforming growth factor receptor and C-X-C motif chemokine ligand 12/C-X-C chemokine receptor type 4 aggravates malignant phenotypes. [PDF]

Oncotarget, 2017
Designated for cyclic shedding, the endometrial stroma is rich in endometrial mesenchymal stem cells (EMSCs) and may play an important role in the development of endometrial carcinoma (EC). This study characterized the crosstalk of EC cells with EMSCs and the resultant effects on malignant phenotypes. The cultured EMSCs expressed CD73, CD90, and CD105,
Ding DC, Chu TY, Liu HW.
europepmc   +4 more sources

Immunological effects of anti-coagulant unfractionated heparin in pregnant Chinese women with cryptic recurrent miscarriages

Archives of Medical Science, 2020
Introduction Anti-coagulant unfractionated heparin of low molecular weight (ACUHlmw) therapy is popularly practised in the therapy of recurrent miscarriages (RMC) due to its anti-coagulant properties.
Yanli Hong, Ke Hong, Xiaojuan Chen, Jinting Xue, Yanyun Yin   +4 more
doaj   +1 more source

Temporal characteristics of astrocytic activation in the TNC in a mice model of pain induced by recurrent dural infusion of inflammatory soup

The Journal of Headache and Pain, 2022
Background Astrocytic activation might play a significant role in the central sensitization of chronic migraine (CM). However, the temporal characteristics of the astrocytic activation in the trigeminal nucleus caudalis (TNC) and the molecular mechanism ...
Leyi Zhang, Chenglong Lu, Li Kang, Yingji Li, Wenjing Tang, Dengfa Zhao, Shengyuan Yu, Ruozhuo Liu   +7 more
doaj   +1 more source

The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape Programs [PDF]

, 2021
Breast cancer (BC) mortality is mainly due to metastatic disease, which is primarily driven by cancer stem cells (CSC). The chemokine C-X-C motif ligand-1 (CXCL1) is involved in BC metastasis, but the question of whether it regulates breast cancer stem ...
Ciummo, Stefania Livia, Todaro, Matilde, Di Carlo, Emma, Fieni, Cristiano, Lanuti, Paola, D’Antonio, Luigi, Stassi, Giorgio, Sorrentino, Carlo   +7 more
core   +1 more source

Ligand-Based NMR Study of C‑X‑C Chemokine Receptor Type 4 (CXCR4)–Ligand Interactions on Living Cancer Cells [PDF]

, 2018
Peptide-binding G protein-coupled receptors (GPCRs) are key effectors in numerous pathological and physiological pathways. The assessment of the receptor-bound conformation of a peptidic ligand within a membrane receptor such as a GPCR is of great impact
Marinelli, Luciana, Salvatore Di Maro, Luigi Portella (458550), Stefania Scala, Luigi Russo, Stefania Scala (458561), Scala, Stefania, Di Maro, Salvatore, Luigi Portella, Francesco Saverio Di Leva, Anna Maria Trotta, Stefano Tomassi (1533535), Diego Brancaccio (1451125), Donatella Diana (2224633), Alfonso Carotenuto (405657), Trotta, Anna Maria, Stefano Tomassi, Ettore Novellino, Fattorusso, Roberto, Luciana Marinelli, Russo, Luigi, Luigi Russo (73534), Anna Maria Trotta (3110427), Brancaccio, Diego, Salvatore Di Maro (405660), Roberto Fattorusso (1616809), Roberto Fattorusso, Luciana Marinelli (1264995), Alfonso Carotenuto, Tomassi, Stefano, Donatella Diana, Francesco Saverio Di Leva (1745107), Carotenuto, Alfonso, Diego Brancaccio, Ettore Novellino (333902), Diana, Donatella, Di Leva, Francesco Saverio, Portella, Luigi, Novellino, Ettore   +38 more
core   +1 more source

Serial Urinary C-C Motif Chemokine Ligand 14 and Risk of Persistent Severe Acute Kidney Injury. [PDF]

, 2023
UNLABELLED: To assess the added prognostic value of serial monitoring of urinary C-C motif chemokine ligand 14 (uCCL14) over that of single measurements, which have been shown to be prognostic for development of persistent severe acute kidney injury (AKI)
Forni, Lui G., Kwan, Thomas, Heung, M, Hoste, Eric, McPherson, Paul, Kwan, T, Kampf, J. Patrick, Kellum, John A., McPherson, P, Marlies, O, Heung, Michael, Kampf, JP, Marlies, Ostermann, Artigas Raventós, Antoni, Hoste, E, Kellum, JA, Forni, LG, Prowle, John R., Bagshaw, Sean M., Chawla, L, Bagshaw, SM, Koyner, Jay L., Prowle, JR, Koyner, JL, Artigas, A, Chawla, Lakhmir S   +25 more
core   +1 more source

Presentation_1_Inhibition of the C-X-C Motif Chemokine 12 (CXCL12) and Its Receptor CXCR4 Reduces Utero-Placental Expression of the VEGF System and Increases Utero-Placental Autophagy.ZIP [PDF]

, 2021
The placenta, a unique organ that only develops during pregnancy, is essential for nutrient, oxygen, and waste exchange between offspring and mother. Yet, despite its importance, the placenta remains one of the least understood organs and knowledge of ...
Ryan L. Ashley (11276376), Elisa Trigo (11276385), Cheyenne L. Runyan (11276379), Marlie M. Maestas (11276382), Gail Silver (11276388)   +4 more
core   +1 more source

NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid [PDF]

, 2018
NI-0801 is a fully human monoclonal antibody against chemokine (C-X-C motif) ligand 10 (CXCL10), which is involved in the recruitment of inflammatory T cells into the liver. The safety and efficacy of NI-0801 was assessed in patients with primary biliary
de Min, Cristina, Walter Ferlin, Marco Carbone, Jones, David E, Adams, David H, Jones, DE, De Min, C, Invernizzi, P, Invernizzi, Pietro, Geneviève Lapeyre, Annarosa Floreani, Paul Richardson, Florence Guilhot, de Graaf, Kathy L, Richardson, Paul, Curbishley, Stuart M, Lapeyre, G, Carbone, Marco, David H. Adams, Ferlin, W, Stephen D. Ryder, Guilhot, F, Moreea, S, Floreani, A, Ferlin, Walter, Chapman, Roger, Roger W. Chapman, Chapman, Roger W, Stuart M. Curbishley, Floreani, Annarosa, Chapman, RW, McCune, C Anne, de Graaf, KL, Carbone, M, Moreea, Sulleman, Curbishley, SM, Sulleman Moreea, McCune, CA, David E. Jones, Adams, DH, Richardson, P, C. Anne McCune, Cristina de Min, Ryder, SD, Kathy L. de Graaf, Ryder, Stephen D, Pietro Invernizzi, Lapeyre, Geneviève, Guilhot, Florence   +48 more
core   +2 more sources