Results 11 to 20 of about 54,862 (115)

Isolation and characterization of cancer-associated fibroblasts in the tumor microenvironment of hepatocellular carcinoma [PDF]

Journal of Liver Cancer, 2023
Background/Aim Cancer-associated fibroblasts (CAFs) play an immunosuppressive role in the tumor microenvironment (TME) of human cancers; however, their characteristics and role in hepatocellular carcinoma (HCC) remain to be elucidated. Methods Nine tumor
Kyoungdo Mun, Jiwon Han, Pureun Roh, Jonggeun Park, Gahee Kim, Wonhee Hur, Jeongwon Jang, Jongyoung Choi, Seungkew Yoon, Youngkyoung You, Hojoong Choi, Pilsoo Sung   +11 more
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The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer

Frontiers in Pharmacology, 2020
Chemokines are a family of small, secreted cytokines which regulate a variety of cell functions. The C-X-C motif chemokine ligand 12 (CXCL12) binds to C-X-C chemokine receptor type 4 (CXCR4) and C-X-C chemokine receptor type 7 (CXCR7). The interaction of
Yi Shi, David J. Riese, Jianzhong Shen
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α1‐Adrenergic Receptors Function Within Hetero‐Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C‐X‐C motif) Receptor 4 in Vascular Smooth Muscle Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundRecently, we provided evidence that α1‐adrenergic receptors (ARs) in vascular smooth muscle are regulated by chemokine (C‐X‐C motif) receptor (CXCR) 4 and atypical chemokine receptor 3 (ACKR3). While we showed that CXCR4 controls α1‐ARs through
Lauren J. Albee, Jonathan M. Eby, Abhishek Tripathi, Heather M. LaPorte, Xianlong Gao, Brian F. Volkman, Vadim Gaponenko, Matthias Majetschak   +7 more
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The clinical usefulness of chemokine C-X-C Motif Ligand 12 as a diagnostic marker for Papillary Thyroid Carcinoma

Indian Journal of Pathology and Microbiology, 2020
Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer worldwide. It is essential to develop methods for the accurate diagnosis of PTC to avoid unnecessary surgery.
Sang Ah Lee, Jae Hyuck Choi, Suk Ju Cho, Jee Won Chang, Young Hee Maeng   +4 more
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Gene Expression Profiling of Peripheral Blood Mononuclear Cells in Type 2 Diabetes: An Exploratory Study

Medicina, 2022
Background and Objectives: Visceral obesity is associated with chronic low-grade inflammation that predisposes to metabolic syndrome. Indeed, infiltration of adipose tissue with immune–inflammatory cells, including ‘classical’ inflammatory M1 and anti ...
Hana M. A. Fakhoury, Muhammad Affan Elahi, Saud Al Sarheed, Mohammed Al Dubayee, Awad Alshahrani, Mahmoud Zhra, Arwa Almassri, Ahmad Aljada   +7 more
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The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone

Tumor Biology, 2017
Most primarily cultured laryngeal squamous cell carcinoma cells are difficult to propagate in vitro and have a low survival rate. However, in our previous work to establish a laryngeal squamous cell carcinoma cell line, we found that laryngeal cancer ...
Mei Wang, Chunping Wu, Yu Guo, Xiaojuan Cao, Wenwei Zheng, Guo-Kang Fan   +5 more
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The biological role of the CXCL12/CXCR4 axis in esophageal squamous cell carcinoma

Cancer Biology & Medicine, 2021
Esophageal cancer is the eighth most common malignant tumor and the sixth leading cause of cancer-related death worldwide. Esophageal squamous cell carcinoma (ESCC) is the main histological type of esophageal cancer, and accounts for 90% of all cancer ...
Xianxian Wu, Hongdian Zhang, Zhilin Sui, Yang Wang, Zhentao Yu   +4 more
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What is the response profile of deciduous pulp fibroblasts stimulated with E. coli LPS and E. faecalis LTA?

BMC Immunology, 2020
Background Oral fibroblast immunological responses to bacterial stimuli are well known. However, there are few studies about pulp fibroblasts from deciduous teeth (HDPF) responses, which are important for the treatment of pulp infections in children. The
Bella Luna Colombini-Ishikiriama, Thiago Jose Dionisio, Thais Francini Garbieri, Rafaela Alves da Silva, Maria Aparecida Andrade Moreira Machado, Sandra Helena Penha de Oliveira, Vanessa Soares Lara, Andrew Seth Greene, Carlos Ferreira Santos   +8 more
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Salivary cytokine panel indicative of non-small cell lung cancer

Journal of International Medical Research, 2018
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We
Tomonobu Koizumi, Vivek Shetty, Masaki Yamaguchi   +2 more
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A Critical Role of Peptidylprolyl Isomerase A Pseudogene 22/microRNA-197-3p/Peptidylprolyl Isomerase A Axis in Hepatocellular Carcinoma

Frontiers in Genetics, 2021
The burden of hepatocellular carcinoma (HCC) worldwide is increasing over time, while the underlying molecular mechanism of HCC development is still under exploration.
Yuwei Gu, Chao Wang, Shengsen Chen, Shengsen Chen, Jia Tang, Xiaoxiao Guo, Wei Hu, An Cui, Dian Zhang, Kangkang Yu, Mingquan Chen, Mingquan Chen   +11 more
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