Genetic engineering for SIT application: a fruit fly‐focused review
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova +2 more
wiley +1 more source
Unlocking neuronal health: leveraging C. elegans for drug repurposing studies. [PDF]
Gowda S, Kumar A, Topf U.
europepmc +1 more source
Molecular mechanisms of sex determination in Lepidoptera: current status and perspectives
The genetic basis of sex determination in Lepidoptera was discovered in 2014 in the silkworm Bombyx mori. In this model species, the W chromosome‐derived small piRNA called Fem piRNA downregulates the expression of a Z‐linked gene, Masculinizer (Masc), which leads to the default female‐specific splicing of the doublesex gene (dsxF) and thus to female ...
František Marec +2 more
wiley +1 more source
The Accumulation and Distribution of Green Synthesized Silver Nanoparticles with Açaí in C. elegans Do Not Cause Redox Toxicity. [PDF]
Taipe Huisa AJ +11 more
europepmc +1 more source
We carried out functional studies using Dicer‐substrate small interfering RNAs (DsiRNAs), targeting the sex determination genes Cctransformer (Cctra) and Cctransformer‐2 (Cctra‐2) in the Mediterranean fruit fly (Ceratitis capitata). Microinjection of DsiRNAs into XX embryos (0‐1 h old) rapidly triggered the expression of male‐specific Cctra isoforms ...
Gennaro Volpe +20 more
wiley +1 more source
Cohesin forms fountains at active enhancers in C. elegans. [PDF]
Lüthi BN +12 more
europepmc +1 more source
Effect of the microbiome on pathogen susceptibility across four Drosophilidae species
Four Drosophilidae species were used to investigate how variation in the host microbiome influences susceptibility to infection. Microbial composition and abundance differed among species and treatments. The effects of microbiome manipulation on host survival were both species‐ and pathogen‐specific.
Hongbo Sun, Ben Longdon, Ben Raymond
wiley +1 more source
Anticonvulsant effects of novel and repurposed drugs on docetaxel-induced neuropathy in C. elegans. [PDF]
Gonzalez-Lerma PX +3 more
europepmc +1 more source
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong +7 more
wiley +1 more source
The ubiquitin-proteasome pathway mediates selective degradation of unloaded Argonaute proteins in C. elegans. [PDF]
Zhao JM +4 more
europepmc +1 more source

