Results 101 to 110 of about 1,608 (173)

C1GALT1-Specific Chaperone 1 [PDF]

, 2020
openaire   +1 more source

Age‑dependent and post‑intraventricular hemorrhage remodeling of the ependymal glycocalyx in mice

Fluids and Barriers of the CNS
Background The ependymal glycocalyx (Gcx) is a glycan-rich apical structure that lines the ventricular brain surface. It is thought to contribute to cerebrospinal fluid dynamics and brain homeostasis by forming a selective barrier, preserving surface ...
Tomohiro Iida, Kosuke Mori, Hiroyuki Tomita, Kazufumi Ohmura, Kohtaro Taguchi, Ayumi Niwa, Tomohiro Kanayama, Shigeyuki Sugie, Hideshi Okada, Tsuyoshi Izumo, Akira Hara   +10 more
doaj   +1 more source

Mechanism of glycosylation orchestrated by C1GalT1 and ST6GalNAc-I enzymes unveiled by NMR

A O-glicosilação do tipo mucina é um mecanismo complexo altamente regulado pela atividade coordenada de enzimas específicas denominadas glicosiltransferases (GTs).
Grosso, Ana Sofia de Campos
core  

Overexpression of GALNT2 or C1GALT1 in Colorectal Cancer is Associated with Increased T antigen Expression

, 2013
在台灣地區，惡性腫瘤多年蟬聯十大死因榜首，而大腸直腸癌是排名第三的癌症死因。台灣地區的大腸直腸癌發生率仍不斷上升中。腫瘤相關醣抗原Tn和T抗原是O-聚醣的根部結構，在正常的上皮組織中，Tn和T抗原會經由不同醣類轉移酶轉換成更複雜的結構。Tn抗原的表現和大腸直腸癌的腫瘤組織分化程度有關；T抗原陽性的病患伴隨更高的癌症肝轉移率。至今腫瘤組織中大量表現Tn和T抗原的原因仍不明確。我們試圖從合成Tn、T抗原的轉移酶：GalNAc-transferase (GALNT family)、Core 1 ß-3 ...
Fan, Tzu-Han, 范子涵
core  

Henoch-Shöenlein vasküliti etyopatogenezinde C1GALT1 ve ST6GALNAC2 genlerinin yeri ve böbrek tutulumu ile ilişkisi

, 2013
Henoch-Schonlein Vasküliti poligenik bir hastalıktır. Son zamanlarda artan kanıtlar gösterir ki anormal galaktozilasyon sonucu IgA1'de oluşan Ü2,6 sialik asit ve galaktoz bozukluğu HSV ve IgAN'nin patogenezinde rol oynar.
Musayev, Shirkhan
core  

The role of C1GALT1 and ST6GALNAC2 genes i̇n defective glycosylati̇on in the patients with IgA nephropathy

, 2015
IgA Nefropatisi poligenik bir hastalıktır. Son zamanlarda artan kanıtlar, anormal glikozilasyon sonucu IgA1'de oluşan α2,6 sialik asit ve galaktoz bozukluğunun IgAN'nin patogenezinde rol oynadığını göstermektedir.
Toparlak Musayev, Pervin
core  

An in vitro approach for simulating divergent Golgi O-glycosylation of tumor-associated MUC1 from normal MUC1. [PDF]

Nat Commun
Nashed A, Dilsook K, Senapathi T, Naidoo KJ.   +3 more
europepmc   +1 more source

O-linked glycan-dependent gating of TPC2 controls lysosomal excitability and organelle remodeling. [PDF]

Nat Commun
Lin A, Lin NY, Keller M, Schütz R, Wu YZ, Burton W, Kinanti NP, Yao CY, Urban N, Liu YW, Bracher F, Galione A, Hsu HJ, Kuo CY, Chen CC.   +14 more
europepmc   +1 more source

Remote intestinal changes following blast-induced thoracic trauma with transient hemorrhagic shock and hind-limb ischemia. [PDF]

Intensive Care Med Exp
Meisen S, Doerfer L, Mannes M, Palmer A, Hildebrand F, Kleger A, Halbgebauer R, Huber-Lang M.   +7 more
europepmc   +1 more source

Developmental dynamics of crop morphology, microbiota, and mucosal immunity in chickens. [PDF]

J Anim Sci Biotechnol
Zhang F, Lu M, Jiang H, Wang X, Liu Y, Yang X, Ren Z.   +6 more
europepmc   +1 more source