Brain Endothelial Glycocalyx as a Blood-Facing Translational Interface in Alzheimer's Disease: Beyond "Leaky" Barriers Toward Repair-First Stratification. [PDF]
Zhang C, Fang D, Zhang L.
europepmc +1 more source
C1GALT1-specific chaperone 1 promotes malignant phenotypes of colon cancer cells
在合成O-glycan 結構的過程中,Galβ1,3GalNAc稱為T antigen 或Core 1 structure,是一個根部的醣類結構,此結構在正常的表皮組織中會被其他糖類轉換酵素延伸為更長的醣類結構;而在許多的癌症中卻表現著大量的T antigen結構,而此結構被證明可以增加癌細胞轉移到肝臟的機率。C1GalT1是core 1 synthase會將UDP-Gal接到GalNAc-Ser/Thr的結構上形成T antigen;而C1GALT1-specific chaperone 1 ...
林能裕, Lin, Neng-Yu
core
Breaking tolerance in the glomerulus: complement as a driver and therapeutic target in IgA nephropathy. [PDF]
Lu CL, Yang CC, Wu CC, Lu KC.
europepmc +1 more source
Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human goblet cell model HT-29-MTX. [PDF]
Schüßler C +17 more
europepmc +1 more source
Gut microbiota dysbiosis and immune responses: insights from IgA nephropathy and inflammatory bowel disease. [PDF]
Yi L +6 more
europepmc +1 more source
TLR7/9-mediated mucosal innate immune dysregulation in IgA nephropathy. [PDF]
Lee M, Suzuki H, Makita Y, Suzuki Y.
europepmc +1 more source
Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer. [PDF]
Park S +12 more
europepmc +1 more source
GlycoAvatars: bead-coated membrane models for studying the cancer-immune cells interactome. [PDF]
Miranda A +8 more
europepmc +1 more source
Galacto-Oligosaccharides Reshape Mucin <i>O</i>-Glycan Profiles to Enhance Small Intestinal Barrier Development in Early Life. [PDF]
Xu L +8 more
europepmc +1 more source
Sialyl-T Antigen: A Novel Red Blood Cell Determinant for Plasmodium falciparum Invasion. [PDF]
Mikdar M +12 more
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