Results 101 to 110 of about 57,775 (215)
Background Cognitive impairment in schizophrenia, aging, and Alzheimer’s disease is associated with spine and synapse loss from the dorsolateral prefrontal cortex (dlPFC) layer III.
Dibyadeep Datta +7 more
doaj +1 more source
C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of self and non-self ligands via its heterotrimeric globular (gC1q) domain and thus trigger the classical pathway.
Ghai, R +7 more
openaire +2 more sources
Elementary derivations of identities for bilateral basic hypergeometric series
We give elementary derivations of several classical and some new summation and transformation formulae for bilateral basic hypergeometric series. For purpose of motivation, we review our previous simple proof ("A simple proof of Bailey's very-well-poised
Schlosser, M.
core +1 more source
Neutrophil‐reactive autoantibodies in blood donors: Can we expect TRALI?
Abstract Background Transfusion‐related acute lung injury (TRALI) is a clinical condition characterized by acute non‐cardiogenic pulmonary edema during or after transfusion. Despite several mitigation strategies, TRALI remains a leading cause of transfusion‐related deaths.
Stefanie Jehle +7 more
wiley +1 more source
Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study
ABSTRACT Background Sarcopenia is an age‐related condition characterized by progressive muscle mass, strength and physical performance declines, contributing to frailty and adverse health outcomes. Despite increasing interest in molecular biomarkers, longitudinal data with external validation are limited.
Sung Hye Kong +8 more
wiley +1 more source
Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I. +10 more
core
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Algorithms in Allergy: Hereditary Angioedema
Allergy, EarlyView.
Konrad Bork +3 more
wiley +1 more source
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei +10 more
wiley +1 more source
C1q binds to immune complexes to elicit complement-dependent microbial killing and enhance phagocytosis. Besides this classical role, C1q also opsonizes apoptotic cells for clearance by phagocytes. C1q deficiency increases susceptibility to microbial infections and is also associated with elevated autoimmunity as characterized by increased apoptotic ...
Lu, J., Wu, X., Teh, B.K.
openaire +2 more sources

