Results 101 to 110 of about 62,354 (276)
C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of self and non-self ligands via its heterotrimeric globular (gC1q) domain and thus trigger the classical pathway.
Ghai, R +7 more
openaire +2 more sources
Long‐term remission of type B insulin resistance syndrome with immunotherapy: A case report
ABSTRACT We report long‐term remission in a patient with type B insulin resistance achieved with a combination of immunotherapies. A 55‐year‐old Japanese man presented with nocturnal hypoglycemia and cytopenia. He also had postprandial hyperglycemia due to severe insulin resistance, which was difficult to manage using high‐dose insulin and recombinant ...
Erika Egawa +3 more
wiley +1 more source
Elevated Serum Complement C1q Levels After Traumatic Brain Injury [Letter]
Wellingson Silva Paiva,1,2 Josimar Ortiz,1 Robson Luis Amorim2 1Division of Neurosurgery, Department of Neurology, Hospital das Clínicas da Faculdade de Medicina, University of São Paulo, São Paulo, Brazil; 2LIM 62, Laboratory of ...
Paiva WS, Ortiz J, Amorim RL
doaj
Tkachenko polarons in vortex lattices
We analyze the properties of impurities immersed in a vortex lattice formed by ultracold bosons in the mean field quantum Hall regime. In addition to the effects of a periodic lattice potential, the impurity is dressed by collective modes with parabolic ...
Bagnato, V. S. +2 more
core +1 more source
scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu +13 more
wiley +1 more source
High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis [PDF]
Background. Anti-C1q antibodies (anti-C1q) have been shown to correlate positively with systemic lupus erythematosus (SLE) nephritis. Several clinical studies indicated a high negative predictive value, suggesting that active lupus nephritis is rarely ...
Frémeaux-Bacchi, Véronique +12 more
core
A Case of Palmoplantar Vesiculobullous Lesions
JEADV Clinical Practice, EarlyView.
Ali Abid +3 more
wiley +1 more source
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I. +10 more
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