Results 131 to 140 of about 62,354 (276)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Increased C1q binding and arthritis in primary biliary cirrhosis. [PDF]

, 1980
Simon F. Crowe, M G Molloy, Ian D. Wells, Bruce Thompson, E. J. Holborow, E B Hamilton, Roger Williams   +6 more
openalex   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

USP11‐PGAM5 Axis Promotes Neurotoxic Astrocyte Reactivity by Aggravating the mtDNA‐cGAS‐STING Pathway After Intracerebral Hemorrhage

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This study reveals that the deubiquitinase USP11 stabilizes PGAM5, triggering neurotoxic astrocyte transformation after intracerebral hemorrhage. PGAM5 promotes mPTP opening and Drp1 dephosphorylation, synergistically amplifying mtDNA leakage into the cytosol and leading to cGAS–STING hyperactivation.
Jiaqing He, Zijuan Qin, Yaning Cai, Haixiao Liu, Tinghao Wang, Qing Hu, Yanni Xu, Pan Yang, Xun Wu, Yan Qu, Wei Guo   +10 more
wiley   +1 more source

Functional recombinant human complement C1q with different affinity tags

, 2021
Isabelle Bally, Sarah Ancelet, Jean‐Baptiste Reiser, Véronique Rossi, Christine Gaboriaud, Nicole M. Thielens   +5 more
openalex   +2 more sources

Plasma C1q/tumor necrosis factor-related protein-3 concentrations are associated with diabetic peripheral neuropathy [PDF]

, 2022
Ke Lin, Yang Liu, Yuyuan Xiong, Keduo Feng, Zeng Wang, Bo Deng   +5 more
openalex   +1 more source

Binding of complement subcomponent C1q to Streptococcus pyogenes: evidence for interactions with the M5 and FcRA76 proteins [PDF]

, 2006
I. V. Koroleva, Anders G. Sjöholm, Claes Schalén   +2 more
openalex   +1 more source

C1q receptors

Clinical and Experimental Immunology, 2000
P, Eggleton, A J, Tenner, K B, Reid
openaire   +3 more sources

Ethylene Glycol Poisoning With Oxalate Nephropathy and Acute Kidney Injury: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Ethylene glycol (EG) is a hazardous alcohol present in various household and industrial products. After being metabolized by ethanol dehydrogenase and aldehyde dehydrogenase, it can produce glycolate, acetaldehyde, and oxalate, leading to acute kidney injury.
Zhenjian Xu, Yanling Dai, Yanling You, Yanjun Huang, Hong Chen, Hongbo Ye, Shuling Yue, Qiongqiong Yang   +7 more
wiley   +1 more source

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice [PDF]

, 2015
Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Anne-Renee Graham, Eilish Brown, Jesse R. McLean, Melissa A. Hayes, Jonathan A. Beagan, Sarah C. Izen, Eduardo Pérez-Torres, Penelope J. Hallett, Ole Isacson   +12 more
openalex   +1 more source