Results 41 to 50 of about 58,368 (237)
Frontiers in Immunology, 2022 C1q, the recognition molecule of the classical pathway of the complement system, plays a central role in pregnancy. Lack of C1q is characterized by poor trophoblast invasion and pregnancy failure.
Chiara Agostinis +20 more
doaj +1 more source
A central role for C1q/TNF-related protein 13 (CTRP13) in modulating food intake and body weight. [PDF]
, 2013 C1q/TNF-related protein 13 (CTRP13), a hormone secreted by adipose tissue (adipokines), helps regulate glucose metabolism in peripheral tissues. We previously reported that CTRP13 expression is increased in obese and hyperphagic leptin-deficient mice ...
Byerly, Mardi S +5 more
core +2 more sources
Development of C1q Affinity Chromatography for the Study of C1q–IgG Interactions
The Journal of Immunology, 2023 Abstract The classical complement system represents a central effector mechanism of Abs initiated by the binding of C1q to target bound IgG. Human C1q contains six heterotrimeric globular head groups that mediate IgG interaction, resulting in an avidity-driven binding event involving multiple IgG molecules binding a single C1q ...
Michael J E Marshall +7 more
openaire +4 more sources
The complement system at the embryo implantation site: friend or foe?
Frontiers in Immunology, 2012 An inflammatory-like process and vascular remodeling represent the main changes that occur in decidua in the early phase of pregnancy. These changes are partly induced by trophoblast cells that colonize the decidua and are also contributed by the ...
Roberta eBulla +2 more
doaj +1 more source
Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines. [PDF]
, 2012 The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators
Seldin, Marcus M, Wong, G William
core +1 more source
eLife, 2020 The ability of a well-known component of the complement cascade to bind to a variety of receptors has implications for signaling biology, spinal cord injury and, possibly, the evolution of the complement system.
Mark Noble, Christoph Pröschel
openaire +3 more sources
Anti-C1q autoantibodies, novel tests and clinical consequences
Frontiers in Immunology, 2013 Although anti-C1q autoantibodies have been described more than four decades ago a constant stream of papers describing clinical associations or functional consequences highlights that anti-C1q antibodies are still hot and happening.
Michael eMahler +2 more
doaj +1 more source
Counting Additive Decompositions of Quadratic Residues in Finite Fields [PDF]
, 2014 We say that a set $S$ is additively decomposed into two sets $A$ and $B$ if $S = \{a+b : a\in A, \ b \in B\}$. A. S\'ark\"ozy has recently conjectured that the set $Q$ of quadratic residues modulo a prime $p$ does not have nontrivial decompositions ...
E. Shparlinski +3 more
core +1 more source
C1q Levels: A Reliable Biomarker for Differentiating Active and Latent Tuberculosis Infection
International Journal of MycobacteriologyBackground: Tuberculosis (TB) poses a significant public health challenge, particularly because it can exist in an asymptomatic latent phase. Latent TB infection indicates the presence of Mycobacterium tuberculosis without clinical symptoms.
Sepideh Darougar +7 more
doaj +1 more source
Frontiers in Immunology, 2014 The ability of circulating blood monocytes to express C1q receptors (cC1qR and gC1qR)synthesize and secrete the classical pathway proteins C1q, C1r and C1s and their regulator, C1-INH is very well established.
Berhane eGhebrehiwet +4 more
doaj +1 more source