Results 11 to 20 of about 17,249 (148)
Primary membranoproliferative glomerulonephritis: natural history, pathogenesis, and treatment [PDF]
Frontiers in NephrologyPrimary membranoproliferative glomerulonephritis (MPGN) is an ultrarare disease characterized by immunofluorescence microscopy as either immune-complex mediated (IC-MPGN) or C3 glomerulopathy (C3), the latter subdivided by electron microscopy to C3 ...
Edward J. Filippone, John L. Farber
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C3 glomerulonephritis: a new category of glomerulonephritis with etiopathogenic implications
Iatreia, 2015 Introduction: Glomerulonephritis with only deposits of C3 (GN-C3) could involve alteration on the complement alternative pathway.Objective: To describe retrospectively a series of GNC3 cases and to determine the frequency with which patients continue ...
Taborda Murillo, Alejandra +2 more
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C3 Glomerulonephritis Associated with Monoclonal Gammopathy of Renal Significance
Acta Médica Portuguesa, 2021 Introduction: Monoclonal gammopathy of renal significance (MGRS) is described as a hematologic condition characterized by nephrotoxic monoclonal proteins produced by a non-malignant B-cell or plasma cell clone. Nevertheless, MGRS can cause serious renal
Inês Gomes-Alves, Inês Castro-Ferreira
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Pathology of C3 Glomerulopathy [PDF]
Childhood Kidney Diseases, 2019 C3 glomerulopathy is a renal disorder involving dysregulation of alternative pathway complement activation. In most instances, a membranoproliferative pattern of glomerular injury with a prevalence of C3 deposition is observed by immunofluorescence ...
Su-Jin Shin, Yoonje Seong, Beom Jin Lim
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Eculizumab and recurrent C3 glomerulonephritis [PDF]
Pediatric Nephrology, 2013 Hyperactivity of the alternative complement pathway is the principle defect in C3 glomerulopathies (C3G). Eculizumab, a monoclonal antibody that binds C5 to prevent formation of the membrane attack complex, has been shown to be beneficial in some patients with this disease.In this open-label, proof-of-concept efficacy-and-safety study, a patient with ...
Sevgi, Gurkan +5 more
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Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Heterozygous laminin β2 mutation in C3 glomerulopathy
Saudi Journal of Kidney Diseases and Transplantation, 2021 C3 glomerulopathy is usually seen with the presence of C3 nephritic factor, homozygous or heterozygous mutations in the regulatory complement proteins factor H, factor I, or C3. We describe the presence of heterozygous laminin β2 mutation in a patient of
Manish R Balwani +3 more
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C3 glomerulonephritis and CFHR5 nephropathy [PDF]
Nephrology Dialysis Transplantation, 2012 Complement is an important aspect of defence against infection and its activation and regulation are finely balanced. Disordered complement regulation can lead to C3 glomerulonephritis (C3GN), which is characterized by complement (but not immunoglobulin) deposition in the glomerulus of the kidney. Although only recently recognized as a clinical entity,
Daniel P, Gale, Patrick H, Maxwell
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Nefrología (English Edition), 2019 Background: C3 glomerulonephritis is a rare, chronic disease characterized by C3c-dominant staining on renal biopsy and is caused by inherited or acquired alternative complement pathway dysregulation.
Sha-sha Han +5 more
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