Results 41 to 50 of about 243,843 (158)

Unmasking the C3ulprit

Graduate Medical Education Research Journal, 2023
Mentor: Prasanth Ravipati Program: Nephrology Type: Case Report Background: C3 glomerulonephritis (C3GN) is a rare disease with pathology findings typically showing a proliferative pattern with C3 deposition on immunofluorescence (IF) and negative ...
Audai Maayah, Brian Benes, Kathleen Borghoff, Kirk Foster, Prasanth Ravipati   +4 more
doaj   +1 more source

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice

Frontiers in Immunology, 2021
Recombinant human factor H (hFH) has potential for treating diseases linked to aberrant complement regulation including C3 glomerulopathy (C3G) and dry age-related macular degeneration.
Heather Kerr, Heather Kerr, Andrew P. Herbert, Elisavet Makou, Dariusz Abramczyk, Talat H. Malik, Hannah Lomax-Browne, Yi Yang, Yi Yang, Isabel Y. Pappworth, Isabel Y. Pappworth, Harriet Denton, Harriet Denton, Anna Richards, Kevin J. Marchbank, Kevin J. Marchbank, Matthew C. Pickering, Paul N. Barlow, Paul N. Barlow   +18 more
doaj   +1 more source

SLE Presenting With Unilateral Loculated Pleural Effusion in a Young Hypertensive Female: A Rare Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Amrit Tripathi, Ujwal Sah, Saurav Shah, Shivaditya Singh, Surya Raj Nishad   +4 more
wiley   +1 more source

Hydrocephalus and Diffuse Alveolar Hemorrhage as the Initial Manifestation of Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many systems, such as the central nervous system (CNS), cardiovascular, musculocutaneous, renal, and respiratory systems, etc. SLE can occur alone or in association with other autoimmune diseases, especially antiphospholipid syndrome (APS).
Ehsan Adib, Narges Gorbanmaleki, Amirreza Eterafi, Sara Jalali Jivan   +3 more
wiley   +1 more source

Etiopathogenetic, Morphological, Diagnostic and Therapeutic Aspects of Acute Glomerulonephritis: Current Status

Архивъ внутренней медицины, 2020
The review provides up-to-date information on the etiological factors and pathogenic mechanisms of development, morphological changes, clinical and laboratory manifestations of acute glomerulonephritis, as well as therapeutic possibilities for its ...
I. T. Murkamilov, I. S. Sabirov, V. V. Fomin, Zh. A. Murkamilova, K. A. Aytbaev   +4 more
doaj   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Galactose‐Deficient Immunoglobulin A1 Predicts Immunoglobulin A Nephropathy Recurrence After Kidney Transplantation: A Single‐Center Retrospective Study

Organ Medicine, Volume 3, Issue 3, Page 139-147, September 2026.
Serum galactose‐deficient IgA1 levels at 3 and 6 months predicted recurrent IgA nephropathy after kidney transplantation. Recipients without recurrence showed a rapid decline in galactose‐deficient IgA1 after transplantation. Early identification of recurrence risk provided a potential window for targeted post‐transplant intervention.
Ronghai Deng, Wengen Chen, Xinhua Chang, Zehuan Chen, Qianyu Ye, Bowen Xu, Yifang Gao, Suxiong Deng, Xiaolin Yu, Changxi Wang, Xiangjun Liu   +10 more
wiley   +1 more source

Clinicopathological and prognostic study of IgA-dominant postinfectious glomerulonephritis

BMC Nephrology, 2021
Background The clinicopathological and prognostic features of IgA-dominant postinfectious glomerulonephritis and its difference from the primary IgA nephropathy remains to be investigated.
Ziyuan Huang, Bo Chen, Ying Zhou, Yan Liang, Wenxian Qiu, Yinqiu Lv, Xiaokai Ding, Ji Zhang, Chaosheng Chen   +8 more
doaj   +1 more source

Successful Control of Late‐Onset Nephrotic Syndrome in FN1‐Associated Fibronectin Glomerulopathy: A 17‐Year Clinical Course

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Fibronectin glomerulopathy (FNG) is a rare renal disorder characterized by excessive glomerular fibronectin deposition, often associated with variants in the fibronectin 1 (FN1) gene. Clinically, FNG presents with proteinuria, hematuria, and hypertension, and may progress to end‐stage kidney disease.
Nobuhiro Kanazawa, Masayuki Iyoda, Kazuki Abe, Taihei Suzuki, Yoko Shirai, Kenichiro Miura, Kazuho Honda, Hirokazu Honda   +7 more
wiley   +1 more source

Mini review: a unique case of crescentic C3 glomerulonephritis

, 2017
Kidney involvement is an under-recognized complication of non-Hodgkin lymphomas. They occur in a variety of mechanisms and differ widely in their clinical presentation. We take this opportunity to report a case of a 65year-old man who developed a rapidly
Dheda, Shyam, Oliver, Kimberley, Dharmenaan Palamuthusingam, Murty Mantha, Kimberley Oliver, Ketan Bavishi, Bavishi, Ketan, Shyam Dheda, Palamuthusingam, Dharmenaan, Mantha, Murty   +9 more
core   +1 more source