Results 31 to 40 of about 243,843 (158)

Regulating complement in the kidney: insights from CFHR5 nephropathy

Disease Models & Mechanisms, 2011
Complement factor H related protein 5 (CFHR5) nephropathy is a monogenic disorder of complement regulation that is endemic in Cyprus. The disease is characterised by haematuria, C3 glomerulonephritis and kidney failure. Its identification suggests a role
Daniel P. Gale, Matthew C. Pickering
doaj   +1 more source

C4d at Crossroads Between Post-Infectious Glomerulonephritis and C3 Glomerulopathy

International Journal of Nephrology and Renovascular Disease, 2021
Shaarif Bashir,1 Mudassar Hussain,1 Aurangzeb Afzal,2 Usman Hassan,1 Maryam Hameed,1 Sajid Mushtaq1 1Department of Pathology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, 54000, Pakistan; 2Department of Nephrology, Lahore General ...
Bashir S, Hussain M, Afzal A, Hassan U, Hameed M, Mushtaq S   +5 more
doaj  

Concurrent Acute Glomerulonephritis and Retropharyngeal Abscess in 10 Year Boy: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Postinfectious Glomerulonephritis (PIGN) usually follows 1-2 weeks after respiratory tract infection and 4-6 weeks after skin infection. Acute Glomerulonephritis (AGN) is uncommon with simultaneous severe throat infections. We describe a 10-year-old boy
Sudha Yadav, Deepali Garg, Narain Das Vaswani, Jaya Shankar Kaushik, Seema Rohilla   +4 more
doaj   +1 more source

Nonimmunoglobulin C3 activating factor in membranoproliferative glomerulonephritis [PDF]

, 1979
Nonimmunoglobulin C3 activating factor in membranoproliferative glomerulonephritis. Material isolated by cryoprecipitation from the serum of a patient with membranoproliferative glomerulonephritis exhibited alternative complement pathway C3-splitting ...
Lewis, Edmund J., Roberts, Jimmy L., Bartlow, Bruce G.   +2 more
core   +1 more source

Glomerular C4d deposition in proliferative glomerular diseases

Indian Journal of Pathology and Microbiology, 2021
Introduction: The aim of this study was to evaluate the immunohistochemical expression of C4d in native renal biopsies of proliferative glomerular diseases, complement pathways in these diseases, and assess the relationship of C4d with histological and ...
Sarojini Raman, Pallavi Mishra, Ansuman Panigrahi, Nikunj K Rout, Kanakalata Dash   +4 more
doaj   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Prevalence and Risk Factors of Systemic Lupus Erythematosus in Patients With Chronic Cutaneous Lupus: A Bicentric Study Employing Three Classification Criteria

International Journal of Dermatology, EarlyView.
This bicentric study of 95 CCLE patients shows SLE prevalence (21.1%–31.6%) varies significantly by classification criteria. Arthralgia was a consistent independent risk factor across all systems. Our findings support the implementation of systematic risk‐stratified screening protocols for CCLE patients, with particular attention to joint symptoms and ...
Noureddine Litaiem, Syrine Nahali, Maroua Slouma, Mourad Mokni, Faten Zeglaoui   +4 more
wiley   +1 more source

C3 glomerulonephritis in Cape Town, South Africa - a case series [PDF]

, 2023
Background  C3 glomerulonephritis (C3GN) is a rare disease of the alternative complement pathway and is associated with poor kidney and patient outcomes. There are no studies from sub-Saharan Africa.
Chothia, Mogamat-Yazied, Hargey, Irfaan, Coetzee, Liezel, Bates, William   +3 more
core   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

Clinico-Pathogenic Similarities and Differences between Infection-Related Glomerulonephritis and C3 Glomerulopathy

, 2023
Recently, the comprehensive concept of “infection-related glomerulonephritis (IRGN)” has replaced that of postinfectious glomerulonephritis (PIGN) because of the diverse infection patterns, epidemiology, clinical features, and pathogenesis ...
Kazuhiro Takeuchi, Mariko Kamata, Togo Aoyama, Yasuo Takeuchi, Tetsuya Abe, Yukihiro Wada, Sayumi Kawamura, Takashi Oda, Ryoma Miyasaka   +8 more
core   +1 more source