Results 31 to 40 of about 217,483 (203)
Recurrent C3 Glomerulonephritis along with BK-Virus-Associated Nephropathy after Kidney Transplantation: A Case Report. [PDF]
C3 glomerulonephritis (C3GN) is a rare cause of end-stage kidney disease and frequently recurrent in allografts following kidney transplantation (KT). Herein, we describe the case of a kidney transplant recipient who developed recurrent C3GN along with ...
Lim JH +16 more
europepmc +2 more sources
C3 glomerulonephritis associated with monoclonal gammopathy of renal significance: a diagnostic and therapeutic challenge. [PDF]
C3 glomerulopathy represents a heterogeneous group of glomerulopathies characterized by hyperactivity of the alternative complement pathway. Although the pathophysiology is incompletely understood, an association between this disease and monoclonal ...
Beirão B +5 more
europepmc +3 more sources
Effectiveness of mycophenolate mofetil in C3 glomerulonephritis. [PDF]
C3 glomerulonephritis is a clinicopathologic entity defined by the presence of isolated or dominant deposits of C3 on immunofluorescence. To explore the effect of immunosuppression on C3 glomerulonephritis, we studied a series of 60 patients in whom a complete registry of treatments was available over a median follow-up of 47 months.
C. Rabasco +30 more
semanticscholar +4 more sources
C3 Glomerulonephritis Associated with Monoclonal Gammopathy. [PDF]
C3 glomerulonephritis (C3GN) is rare. It is a proliferative glomerulonephritis resulting from glomerular deposition of complement factors due to dysregulation of the alternative pathway of complement. The association between monoclonal protein production and development of C3GN was described.
Piedade AD +4 more
europepmc +3 more sources
Cat-Scratch Disease Masquerading as C3 Glomerulonephritis. [PDF]
Sutu B +6 more
europepmc +5 more sources
C3 glomerulonephritis and CFHR5 nephropathy [PDF]
Complement is an important aspect of defence against infection and its activation and regulation are finely balanced. Disordered complement regulation can lead to C3 glomerulonephritis (C3GN), which is characterized by complement (but not immunoglobulin) deposition in the glomerulus of the kidney. Although only recently recognized as a clinical entity,
Daniel P, Gale, Patrick H, Maxwell
openaire +2 more sources
Eculizumab and recurrent C3 glomerulonephritis. [PDF]
Hyperactivity of the alternative complement pathway is the principle defect in C3 glomerulopathies (C3G). Eculizumab, a monoclonal antibody that binds C5 to prevent formation of the membrane attack complex, has been shown to be beneficial in some patients with this disease.In this open-label, proof-of-concept efficacy-and-safety study, a patient with ...
Gurkan S +5 more
europepmc +4 more sources
Heterozygous laminin β2 mutation in C3 glomerulopathy
C3 glomerulopathy is usually seen with the presence of C3 nephritic factor, homozygous or heterozygous mutations in the regulatory complement proteins factor H, factor I, or C3. We describe the presence of heterozygous laminin β2 mutation in a patient of
Manish R Balwani +3 more
doaj +1 more source
Background: C3 glomerulonephritis is a rare, chronic disease characterized by C3c-dominant staining on renal biopsy and is caused by inherited or acquired alternative complement pathway dysregulation.
Sha-sha Han +5 more
doaj +3 more sources

