Results 21 to 30 of about 243,843 (158)

Case Report: Clinical and Pathological Findings of a Recurrent C3 Glomerulopathy With Superimposed Membranoproliferative Glomerulonephritis Pattern and Cryoglobulinemia Associated With COVID-19

Frontiers in Pediatrics, 2022
Coronavirus disease 2019 (COVID-19) may cause a wide spectrum of kidney pathologies. The impact of COVID-19 is unclear in the context of the complement system abnormalities, including C3 glomerulopathy (C3G).
Nastaran Daneshgar, Peir-In Liang, Peir-In Liang, Christina J. Michels, Carla M. Nester, Carla M. Nester, Lyndsay A. Harshman, Dao-Fu Dai   +7 more
doaj   +1 more source

Immune complex glomerulonephritis in C4- and C3-deficient mice [PDF]

, 1998
Immune complex glomerulonephritis in C4- and C3-deficient mice. In this study, we examined the roles of C4 and C3 in immune complex glomerulonephritis by actively immunizing C4-deficient (C4 –/–), C3 deficient (C3 –/–) and wild-type mice with apoferritin.
Alexander, Jessy J., Chun He, Carroll, Michael C., Mark Haas, Richard J. Quigg, Alice Lim, Jessy J. Alexander, Michael C. Carroll, Haas, Mark, He, Chun, Quigg, Richard J., Lim, Alice   +11 more
core   +1 more source

C3 Glomerulonephritis: A Rare Case of GN [PDF]

, 2020
C3 Glomerulonephritis has undergone a recent change in its definition since its consensus review in 2013. Prior to 2013, C3GN would have been classified as a Type 3 Membranoproliferative Glomerulonephritis with the classic pathologic feature of double ...
Shaban, Hesham, Linder, Stanley
core   +1 more source

Eculizumab as a New Treatment for Severe Acute Post-infectious Glomerulonephritis: Two Case Reports

Frontiers in Medicine, 2021
Acute post-infections glomerulonephritis (APIGN) is a frequent cause of glomerulonephritis and represents the most common cause of acute glomerulonephritis in children.
Hassib Chehade, Gabriella Guzzo, Gabriella Guzzo, Gabriella Guzzo, Francois Cachat, Samuel Rotman, Daniel Teta, Giuseppe Pantaleo, Salima Sadallah, Amita Sharma, Ivy A. Rosales, Nina Tolkoff-Rubin, Manuel Pascual   +12 more
doaj   +1 more source

Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report

BMC Nephrology, 2018
Background Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway.
Shuma Hirashio, Ayaka Satoh, Takahiro Arima, Kouichi Mandai, Tadasuke Awaya, Kumi Oshima, Shigeo Hara, Takao Masaki   +7 more
doaj   +1 more source

C3 Glomerulopathy: A Rare Entity with Future Directions

Revista Portuguesa de Nefrologia e Hipertensão, 2023
C3 glomerulopathies are a rare group of glomerular diseases resulting from excessive activation of the alternative complement pathway. The pathogenesis involves genetic, acquired, or immunologic defects in regulators of the alternative complement ...
Sara Vilela, Catarina Cardoso, Sara Barreto, Gonçalo Cruz, Pedro Bravo, Cristina Santos   +5 more
doaj   +1 more source

What is new in the management of rapidly progressive glomerulonephritis? [PDF]

, 2015
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, G. H. B. Greenhall, Salama, AD, A. D. Salama   +3 more
core   +1 more source

FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy

Frontiers in Immunology, 2021
BackgroundFactor H-related protein 5 (FHR-5) is a member of the complement Factor H protein family. Due to the homology to Factor H, the main complement regulator of the alternative pathway, it may also be implicated in the pathomechanism of kidney ...
Nóra Garam, Marcell Cserhalmi, Zoltán Prohászka, Zoltán Prohászka, Ágnes Szilágyi, Nóra Veszeli, Nóra Veszeli, Edina Szabó, Barbara Uzonyi, Attila Iliás, Christof Aigner, Alice Schmidt, Martina Gaggl, Gere Sunder-Plassmann, Dóra Bajcsi, Jürgen Brunner, Alexandra Dumfarth, Daniel Cejka, Stefan Flaschberger, Hana Flögelova, Ágnes Haris, Ágnes Hartmann, Andreas Heilos, Thomas Mueller, Krisztina Rusai, Klaus Arbeiter, Johannes Hofer, Johannes Hofer, Johannes Hofer, Dániel Jakab, Mária Sinkó, Erika Szigeti, Csaba Bereczki, Viktor Janko, Kata Kelen, György S. Reusz, Attila J. Szabó, Nóra Klenk, Krisztina Kóbor, Nika Kojc, Maarten Knechtelsdorfer, Mario Laganovic, Adrian Catalin Lungu, Anamarija Meglic, Rina Rus, Tanja Kersnik Levart, Ernesta Macioniene, Marius Miglinas, Anna Pawłowska, Tomasz Stompór, Ludmila Podracka, Michael Rudnicki, Gert Mayer, Romana Rysava, Jana Reiterova, Marijan Saraga, Marijan Saraga, Tomáš Seeman, Jakub Zieg, Eva Sládková, Natasa Stajic, Tamás Szabó, Andrei Capitanescu, Simona Stancu, Miroslav Tisljar, Kresimir Galesic, András Tislér, Inga Vainumäe, Martin Windpessl, Tomas Zaoral, Galia Zlatanova, Mihály Józsi, Mihály Józsi, Dorottya Csuka, Dorottya Csuka   +74 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

IgA Vasculitis and C3 Glomerulonephritis: One Patient... Various Autoimmune Diseases

Gazeta Médica, 2022
Leucocytoclastic vasculitis refers to a small vessel vasculitis caused by immune complexes, infections and medications. IgA or IgM/IgG immune complexes can be found in direct immunofluorescence studies suggesting specific forms of leucocytoclastic ...
Ana Margarida Pedro Antunes Ferreira Gaudêncio, Ana Catarina Lameiras, Teresa Mendonça   +2 more
doaj   +4 more sources