Results 11 to 20 of about 243,843 (158)
C3 glomerulopathy (C3GP) is a group of diseases caused by a deregulated complement system, which encompasses both dense deposit disease and C3 glomerulonephritis.
Lalani De Silva +2 more
doaj +2 more sources
C3 deposits worsens the prognosis in type iii extracapillary glomerulonephritis
Introduction: Type iii extracapillary glomerulonephritis (PEGN) is a common cause of rapidly progressive glomerulonephritis and it is usually associated with circulating anti-neutrophil cytoplasmic antibodies (ANCAs). Recent evidence points to complement
Marina Sánchez-Agesta Martínez +6 more
doaj +2 more sources
C3 glomerulonephritis: a new category of glomerulonephritis with etiopathogenic implications [PDF]
Introduction: Glomerulonephritis with only deposits of C3 (GN-C3) could involve alteration on the complement alternative pathway.Objective: To describe retrospectively a series of GNC3 cases and to determine the frequency with which patients continue ...
Taborda Murillo, Alejandra +2 more
doaj +1 more source
Pembrolizumab induced-C3 glomerulonephritis and RBC cast nephropathy: a case report. [PDF]
Background Immune checkpoint inhibitors (ICIs) are increasingly being used in the treatment of several cancers. Pembrolizumab is an anti-programmed cell death-1 (anti-PD-1) monoclonal antibody that is approved for the treatment of metastatic non-small ...
Yang Z, Xu H, Gou S, Wu H, Hu Z.
europepmc +2 more sources
C3 glomerulonephritis associated with monoclonal gammopathy of renal significance: a diagnostic and therapeutic challenge. [PDF]
C3 glomerulopathy represents a heterogeneous group of glomerulopathies characterized by hyperactivity of the alternative complement pathway. Although the pathophysiology is incompletely understood, an association between this disease and monoclonal ...
Beirão B +5 more
europepmc +4 more sources
Background: C3 glomerulonephritis is a rare, chronic disease characterized by C3c-dominant staining on renal biopsy and is caused by inherited or acquired alternative complement pathway dysregulation.
Sha-sha Han +5 more
doaj +3 more sources
Immune Complex-Mediated Crescentic Glomerulonephritis [PDF]
Immune complex-mediated Glomerulonephritis (GN) comprises a group of disorders including Immunoglobulin A (IgA) nephropathy, IgA vasculitis, lupus nephritis, infection-related GN {poststreptococcal, Hepatitis C Virus (HCV)}, and fibrillary GN with ...
Dhruvi Reddy +2 more
doaj +1 more source
Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance [PDF]
Complement activation is known to have deleterious effects on organ transplantation. On the other hand, the complement system is also known to have an important role in regulating immune responses.
Cook, T +21 more
core +1 more source
C3 glomerulonephritis: Two pediatric cases
C3 glomerulopathy defi nes a group of diseases characterized with deposition of C3 alone in the glomeruli in the absence of deposition of immunoglobulin or other complement products.
Alaygut, Demet +5 more
core +3 more sources
C3 Glomerulopathy: recent advances and an update on management [PDF]
C3 glomerulopathy (C3G) is a clinicopathologic entity characterized by glomerular inflammation with dominant staining for C3 on immunofluorescence microscopy.
Lilian Monteiro Pereira Palma +2 more
doaj +4 more sources

