Diverse Clinical Presentations of C3 Dominant Glomerulonephritis [PDF]
Frontiers in Medicine, 2020 C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic immune complex membranoproliferative glomerulonephritis (iMPGN).
Ramy M. Hanna +13 more
doaj +7 more sources
Timing of eculizumab therapy for C3 glomerulonephritis. [PDF]
Clin Kidney J, 2015 Eculizumab is an anti-C5 antibody that inhibits C5 cleavage and prevents the generation of the terminal complement complex C5b-9. Eculizumab is licensed to treat paroxysmal nocturnal haemoglobinuria or atypical haemolytic uraemic syndrome (aHUS ...
Rodriguez-Osorio L, Ortiz A.
europepmc +4 more sources
C3 glomerulonephritis: a new category of glomerulonephritis with etiopathogenic implications [PDF]
Iatreia, 2015 Introduction: Glomerulonephritis with only deposits of C3 (GN-C3) could involve alteration on the complement alternative pathway.Objective: To describe retrospectively a series of GNC3 cases and to determine the frequency with which patients continue ...
Taborda Murillo, Alejandra +2 more
doaj +2 more sources
Refractory C3 glomerulonephritis unresponsive to bortezomib
NefrologíaTaha Enes Cetin +4 more
doaj +4 more sources
Pathology of C3 Glomerulopathy [PDF]
Childhood Kidney Diseases, 2019 C3 glomerulopathy is a renal disorder involving dysregulation of alternative pathway complement activation. In most instances, a membranoproliferative pattern of glomerular injury with a prevalence of C3 deposition is observed by immunofluorescence ...
Su-Jin Shin, Yoonje Seong, Beom Jin Lim
doaj +4 more sources
C3 Glomerulonephritis Post COVID-19 Vaccination: A Case Report and Review of the Literature [PDF]
Brown Journal of Hospital Medicine, 2022 COVID-19 vaccines are safe and effective at preventing severe illness of COVID -19. There are increasing reports of glomerulonephritis post COVID-19 vaccination.
Arjun Sekar +2 more
doaj +2 more sources
Case Reports in Nephrology, 2021 C3 glomerulopathy (C3GP) is a group of diseases caused by a deregulated complement system, which encompasses both dense deposit disease and C3 glomerulonephritis.
Lalani De Silva +2 more
doaj +2 more sources
Concurrent anti-neutrophil cytoplasmic antibody-associated glomerulonephritis and IgG4-associated tubulointerstitial nephritis with C3 glomerulonephritis: A case report. [PDF]
Medicine (Baltimore), 2020 Rationale: IgG4-related disease (IgG4-RD) is a slowly progressing inflammatory disease that can involve multiple organ systems. There is considerable overlap between IgG4-RDs and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV ...
Feng J +6 more
europepmc +2 more sources
C3 glomerulonephritis: two pediatric cases
Paediatria Croatica, 2013 C3 glomerulopathy defi nes a group of diseases characterized with deposition of C3 alone in the glomeruli in the absence of deposition of immunoglobulin or other complement products. These diseases include dense deposit disease, type 1 membranoproliferative glomerulonephritis (MPGN), familial type 3 MPGN, familial C3 glomerulonephritis associated with ...
Alaygut, Demet +5 more
core +4 more sources
Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis. [PDF]
BMC Nephrol, 2019 BackgroundC3 glomerulonephritis (C3GN) is a rare disease caused by inherited or acquired complement alternative pathway (CAP) dysregulation, which could also be secondary to monoclonal gammopathy of undetermined significance (MGUS).
Li LL +8 more
europepmc +2 more sources