Results 61 to 70 of about 17,249 (148)

Acute Acalculous Cholecystitis as the First Manifestation of Systemic Lupus Erythematosus in a Young Man: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Acute acalculous cholecystitis can rarely be the initial manifestation of systemic lupus erythematosus. Awareness of this atypical presentation is essential to avoid unnecessary surgical intervention. Prompt recognition and initiation of immunosuppressive therapy may resolve symptoms and help establish the correct underlying diagnosis.
Mohammad Mehdi Shadravan, Arman Ahmadzadeh, Ilad Alavi Darazam, Shahriar Nikpour, Maryam Haghighi Morad, Farid Javandoust Gharebagh, Sadaf Mahmoodkalaye, Setareh Mahmoodi, Legha Lotfollahi   +8 more
wiley   +1 more source

Expanded Phenotype of PAX2‐Related Papillorenal Syndrome: A Case Featuring FSGS, Atypical Retinopathy, Cerebellar Hypoplasia, and ADHD

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Papillorenal syndrome (PAPRS), or renal coloboma syndrome, is a rare autosomal dominant disorder caused by PAX2 mutations. It classically manifests with renal hypodysplasia and optic nerve anomalies. However, recent literature suggests an expanding phenotypic spectrum.
Nadira Sultana, Abdullah Al Mamun, Afroza Begum   +2 more
wiley   +1 more source

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley   +1 more source

Nephrotic syndrome associated with hepatointestinal schistosomiasis Síndrome nefrótica associada à esquistossomose hepatointestinal

Revista do Instituto de Medicina Tropical de São Paulo, 1992
Schistosomal nephropathy has long been related to the hepatosplenic form of schistosomiasis. In the last few years, 24 patients with hepatointestinal schistosomiasis and the nephrotic syndrome were studied.
H. Abensur, I. Nussenzveig, L.B. Saldanha, M.S.C. Petalozzi, M.T. Barros, M. Marcondes, R.T. Barros   +6 more
doaj   +1 more source

Influenza a H1N1 associated acute glomerulonephritis in an adolescent

IDCases, 2020
Influenza virus primarily affects the respiratory system. It rarely causes extrapulmonary complications, with otitis media and febrile seizures being the most common in children.
Garyfallia Syridou, Ioannis Drikos, Artemis Vintila, Antigoni Pegkou, Loukia Zografou, Panagiotis Roungas, Eleni Papa, Dimitris Kyriazopoulos, Olga Savelieva, Eleni Antonopoulou   +9 more
doaj   +1 more source

Risk Factors of Disease Progression in IgA Nephropathy: A Systematic Review and Meta‐Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Objective IgA nephropathy (IgAN) is an important cause of chronic renal failure, and nearly all patients with IgAN are at risk of developing to end‐stage renal disease (ESRD) during their lifetime. This meta‐analysis aimed to identify and evaluate risk factors associated with the progression of IgAN patients.
Dan Xu, Minjie Zhang, Weiwei Liang, Lijiang Fang, Feifei Ge   +4 more
wiley   +1 more source

C3 glomerulopathy associated with mycoplasma pneumoniae infection and positive IgA staining

BMC Nephrology
Background Patients with C3 glomerulopathy (C3G) often have a history of infection, which implies that infection may lead to abnormal activation of the complement alternative pathway (CAP) and induce the development of C3G.
Zhi-Yu Duan, Ji-Jun Li, Guang-Yan Cai, SuXia Wang, XuanLi Tang, WanYin Hou, Lei Jiang, Yan Song   +7 more
doaj   +1 more source

Evaluating the utility of anti-human IgA, IgG, IgM, Kappa, Lambda-FITC (conjugate) cocktail antibody in transplant renal pathology

Surgical and Experimental Pathology
In this study, we evaluated the utility of polyclonal rabbit anti-human IgA, IgG, IgM, Kappa, Lambda - FITC antibody cocktail (CTA) in identifying immune complex deposits in conjunction with C3 & C1q antibodies in consecutive transplant renal biopsies. A
Shilpi Thakur, Venkatesh Dhanasekaran, Balan Louis Gaspar   +2 more
doaj   +1 more source

Principles for Optimal Drug Selection in IgA Nephropathy—Time for Integrating Pathogenesis and Clinical Markers to Guide Therapy

Nephrology, Volume 31, Issue 2, February 2026.
ABSTRACT IgA nephropathy is a progressive glomerular disease with a variable clinical course and a substantial risk of progression to end‐stage kidney failure. While proteinuria has long been the central therapeutic target, insights into disease pathogenesis indicate that haematuria should also guide treatment decisions. Based on the pathophysiology of
Yusuke Suzuki
wiley   +1 more source

Full‐House Nephropathy Without Lupus Manifesting During Acute Kidney Allograft Rejection: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley   +1 more source