Results 71 to 80 of about 24,964 (213)

#627 C3 glomerulonephritis and C3-dominant infection related glomerulonephritis—are they similar?

Nephrology Dialysis Transplantation
Abstract Background C3 glomerulonephritis (C3GN) and C3 dominant infection related glomerulonephritis (C3-IRGN) comprise two important immune complex mediated diseases. C3GN is caused by dysregulation of the alternate pathway by congenital or acquired abnormalities in the complement pathway.
Mythri Shankar, Ranjitha Siddalingappa, Sreedhara C.G., Kishan A., Karthik Tenannkore   +4 more
openaire   +1 more source

A case of glomerulonephritis with dominant C3 with organized deposits complicated by non-tuberculous mycobacteria

Human Pathology Reports
We report a case of membranoproliferative glomerulonephritis (MPGN) with dominant C3 and uniquely organized deposits complicated by pulmonary non-tuberculous mycobacterial (NTM) infection.
Masanori Sudo, Chihiro Sakurazawa, Yuichi Sakamaki, Masato Habuka, Asa Ogawa, Yumi Ito, Naofumi Imai, Sayuri Takamura, Satoshi Ito, Akira Shimizu, Shin Goto, Suguru Yamamoto   +11 more
doaj   +1 more source

C4 nephritic factor in patients with immune-complex-mediated membranoproliferative glomerulonephritis and C3-glomerulopathy

Orphanet Journal of Rare Diseases, 2019
Background Acquired or genetic abnormalities of the complement alternative pathway are the primary cause of C3glomerulopathy(C3G) but may occur in immune-complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) as well. Less is known about the
Nóra Garam, Zoltán Prohászka, Ágnes Szilágyi, Christof Aigner, Alice Schmidt, Martina Gaggl, Gere Sunder-Plassmann, Dóra Bajcsi, Jürgen Brunner, Alexandra Dumfarth, Daniel Cejka, Stefan Flaschberger, Hana Flögelova, Ágnes Haris, Ágnes Hartmann, Andreas Heilos, Thomas Mueller, Krisztina Rusai, Klaus Arbeiter, Johannes Hofer, Dániel Jakab, Mária Sinkó, Erika Szigeti, Csaba Bereczki, Viktor Janko, Kata Kelen, György S. Reusz, Attila J. Szabó, Nóra Klenk, Krisztina Kóbor, Nika Kojc, Maarten Knechtelsdorfer, Mario Laganovic, Adrian Catalin Lungu, Anamarija Meglic, Rina Rus, Tanja Kersnik-Levart, Ernesta Macioniene, Marius Miglinas, Anna Pawłowska, Tomasz Stompór, Ludmila Podracka, Michael Rudnicki, Gert Mayer, Romana Rysava, Jana Reiterova, Marijan Saraga, Tomáš Seeman, Jakub Zieg, Eva Sládková, Tamás Szabó, Andrei Capitanescu, Simona Stancu, Miroslav Tisljar, Kresimir Galesic, András Tislér, Inga Vainumäe, Martin Windpessl, Tomas Zaoral, Galia Zlatanova, Dorottya Csuka   +60 more
doaj   +1 more source

Safety and Efficacy of Obinutuzumab in Treating Lupus Nephritis: A Systematic Review

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE), often leading to end‐stage renal disease. Despite current immunosuppressive therapies, complete renal remission remains limited. Obinutuzumab, a type II anti‐CD20 monoclonal antibody, offers enhanced B‐cell depletion compared to type I antibodies ...
Zainab Arif, Hafsa Ali, Erum Siddiqui, Shorrem Naeem, Mohammed Hammad Jaber Amin   +4 more
wiley   +1 more source

Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion [PDF]

Kidney International, 2012
Membranoproliferative glomerulonephritis (MPGN) denotes a general pattern of glomerular injury that is easily recognized by light microscopy. With additional studies, MPGN subgrouping is possible. For example, electron microscopy resolves differences in electron-dense deposition that are classically referred to as MPGN type I (MPGN I), MPGN II, and ...
Sethi, Sanjeev, Nester, Carla M., Smith, Richard J.H.   +2 more
openaire   +2 more sources

Membranoproliferative glomerulonephritis associated with type II cryoglobulinaemia in a renal transplant patient with hepatitis C [PDF]

, 2014
The most common HCV-related nephropathy is membranoproliferative glomerulonephritis (MPGN), usually in the context of cryoglobulinaemia. The treatment of this entity is not consensual and represents a challenge to clinicians.
Almeida, M., Bento, C., Castro-Henriques, A., Dias, L., Malheiro, J., Martins, L., Vizcaíno, J.   +6 more
core  

Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis [PDF]

Clinical Journal of the American Society of Nephrology, 2012
Summary Background and objectives The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the alternative complement pathway. Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, may prove beneficial.
Andrew S, Bomback, Richard J, Smith, Gaetano R, Barile, Yuzhou, Zhang, Eliot C, Heher, Leal, Herlitz, M Barry, Stokes, Glen S, Markowitz, Vivette D, D'Agati, Pietro A, Canetta, Jai, Radhakrishnan, Gerald B, Appel   +11 more
openaire   +2 more sources

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Autoimmune disorder patients are vulnerable to cytomegalovirus (CMV) infections, which can present with symptoms that mimic flare‐ups of the underlying disease. We present two cases: a 44‐year‐old woman with systemic lupus erythematosus and a 55‐year‐old man with sarcoidosis, both of whom developed unusual manifestations linked to CMV infection ...
Elaheh Karimi, Zahra Moradi, Somayeh Soroureddin, Ozra Nouri, Zahra Tamartash, Hoda Kavosi   +5 more
wiley   +1 more source

Durable remission of C3 glomerulonephritis with mycophenolate mofetil [PDF]

Nephrology, 2017
AbstractIn C3 glomerulopathy, uncontrolled complement C3 activation via the alternative pathway results in glomerular C3 deposition and, in many cases, progressive renal failure. Despite advances in understanding of C3G pathogenesis over the last few years, there are no proven treatments.
Nicole, Lioufas, Moira, Finlay, Thomas, Barbour   +2 more
openaire   +2 more sources