Results 81 to 90 of about 4,362 (171)

Monoclonal Antibodies for the Treatment of the C3 Glomerulopathies [PDF]

Clinical Journal of the American Society of Nephrology, 2012
Our understanding of glomerular disease has been steadily progressing from pattern-based histologic classification and empirical immunosuppressive treatments to better molecular characterization of disease and, albeit more slowly, to more targeted therapies.
openaire   +2 more sources

Proof of concept of a new plasma complement Factor H from waste plasma fraction

Frontiers in Immunology
IntroductionComplement factor H (FH) is a major regulator of the complement alternative pathway, its mutations predispose to an uncontrolled activation in the kidney and on blood cells and to secondary C3 deficiency.
Filippo Mori, Giancarlo Pascali, Giancarlo Pascali, Silvia Berra, Alessandra Lazzarotti, Daniele Panetta, Silvia Rocchiccioli, Elisa Ceccherini, Francesco Norelli, Antonio Morlando, Roberta Donadelli, Alberto Clivio, Claudio Farina, Marina Noris, Piero A. Salvadori, Giuseppe Remuzzi   +15 more
doaj   +1 more source

C3 glomerulopathy

Nephrology Dialysis Transplantation, 2019
Koopman, J.J.E., Vries, A.P.J. de, Bajema, I.M.   +2 more
openaire   +3 more sources

C3 glomerulopathy triggered by infection-A rare case report

Asian Journal of Medical Sciences
C3 glomerulopathy (C3G) is a rare condition caused by dysregulation of the alternative complement pathway. Although a link between Group A streptococcal infection and C3G has been proposed, underlying complement abnormalities—genetic or acquired—are ...
Diksha Samsukha , Rohidas T Borse, Nagnath Redewad , Meenal Chandanwale   +3 more
doaj   +1 more source

Recent advances in C3 glomerulopathy with monoclonal gammopathy

Linchuang shenzangbing zazhi
As a rare monoclonal gammopathy, C3 glomerulopathy with monoclonal gammopathy （C3G-MIg） is a major cause of renal injury in patients aged over 50 years. The key pathogenesis of C3G-MIg is that monoclonal immunoglobulins act as an autoantibody or directly
Yi-lan Cheng, Lu Zhang, Hui-ming Wang
doaj   +1 more source

Dense deposit disease in a child with febrile sore throat

Saudi Journal of Kidney Diseases and Transplantation, 2017
Dense deposit disease or membranoproliferative glomerulonephritis type II is a rare glomerulopathy characterized on renal biopsy by deposition of abnormal electron-dense material in the glomerular basement membrane.
Giovanni Conti, Dominique De Vivo, Agata Vitale, Carmelo Fede, Domenico Santoro   +4 more
doaj  

C3 glomerulonephritis: a new category of glomerulonephritis with etiopathogenic implications

Iatreia, 2015
Introduction: Glomerulonephritis with only deposits of C3 (GN-C3) could involve alteration on the complement alternative pathway.Objective: To describe retrospectively a series of GNC3 cases and to determine the frequency with which patients continue ...
Taborda Murillo, Alejandra, Arroyave Suárez, Mariam José, Arias, Luis Fernando   +2 more
doaj  

Clinical characteristics and short term outcomes of childhood immune complex membranoproliferative glomerulonephritis and C3 glomerulopathy: a single centre retrospective study

BMC Nephrology
Background Membranoproliferative glomerulonephritis, with its immune complex variety and C3 glomerulopathy, is a rare glomerular disease in children. The objective of this study was to determine the clinical features and short-term outcomes in children ...
Irshad Ali Bajeer, Sabeeta Khatri, Pawan Kumar, Seema Hashmi, Mohammed Mubarak, Ali Asghar Lanewala   +5 more
doaj   +1 more source

Does pregnancy modify disease activity in C3 glomerulopathy? [PDF]

CEN Case Rep
Yamaguchi Y, Okabayashi Y, Okabe M, Tsuboi N, Yokoo T.   +4 more
europepmc   +1 more source

C3 Glomerulopathy: recent advances and an update on management. [PDF]

J Bras Nefrol
Palma LMP, Barbosa MINH, Sethi S.
europepmc   +1 more source