Results 81 to 90 of about 216,693 (188)

Pediatric Non‐Lupus Full House Nephropathy: Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Lupus nephritis is a severe manifestation of systemic lupus erythematosus (SLE) typically characterized by glomerular “full‐house” immunofluorescence. However, non‐lupus nephropathies may occasionally exhibit similar patterns, creating diagnostic uncertainty.
Mohammad Firoz Anjum, Suraj Sah, Inesh Khanal, Sharmila Gainju, Sri Ram K.C.   +4 more
wiley   +1 more source

The many faces of C3 glomerulopathy [PDF]

Kidney International, 2012
To the Editor: The recent article by Sethi et al., ‘Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion’, made me revisit a 12-year-old publication. In ‘Apparent progression of acute glomerulonephritis to dense deposit disease’ we described an 8-year-old boy with hypocomplementemia and meningococcemia.
openaire   +2 more sources

Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

Kidney International Reports, 2019
Introduction: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood.
Nicholas R. Medjeral-Thomas, Hilary Moffitt, Hannah J. Lomax-Browne, Nicholas Constantinou, Tom Cairns, H. Terence Cook, Matthew C. Pickering   +6 more
doaj   +1 more source

Xenotransplantation Literature Update: July–December 2025

Xenotransplantation, Volume 33, Issue 2, March/April 2026.
ABSTRACT The second half of 2025 marked a significant transition for xenotransplantation, shifting further from experimental feasibility to early clinical translation. Prolonged physiologic support from genetically engineered porcine kidneys and livers in human recipients provided unprecedented insight into organ compatibility, rejection dynamics, and ...
Kasra Shirini, Joseph M. Ladowski, Niket Harsh, Raphael P. H. Meier   +3 more
wiley   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

American Journal of Hematology, Volume 101, Issue 2, Page 242-254, February 2026.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth, Wilma Barcellini, Christine Ademokun, Junho Jang, Maria Luisa Lozano, David Valcarcel Ferreiras, Cristina Pascual‐Izquierdo, Shripad Chitnis, Sofiya Matviykiv, Alessandra Vitaliti, Chi Chen, Vasiliki Katsanou, Raghav Chawla, Hanny Al‐Samkari   +13 more
wiley   +1 more source

C3 glomerulopathy associated with peripheral retinal drusen: Case report and review of the literature

Indian Journal of Ophthalmology. Case Reports
A 46-year-old female was admitted with complaints of fever and generalized bodily swelling and a working phenotypic diagnosis of nephrotic syndrome. Renal function was mildly impaired.
Salil Mehta, Juhi Bhargava, Hemant Mehta
doaj   +1 more source

Case Report of Spontaneous Remission of Biopsy-Proven Idiopathic Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Case Reports in Nephrology and Dialysis, 2017
Membranoproliferative glomerulonephritis (MPGN) is a histopathologic diagnosis causing microscopic hematuria, nephrotic range proteinuria, and chronic renal failure.
Rehan Shah, Mark S. Segal, Michael J. Wilkowski   +2 more
doaj   +1 more source

Mycophenolate Mofetil in Combination with Steroids for Treatment of C3 Glomerulopathy

, 2018
Background and objectives C3 glomerulopathy is a form of complement-mediated GN. Immunosuppressive therapy may be beneficial in the treatment of C3 glomerulopathy. Mycophenolate mofetil is an attractive treatment option given its role in the treatment of
Rupali S. Avasare, Yasemin Ozluk, Gerald B. Appel, Ozluk, Yasemin, Appel, Gerald B., Andrew S. Bomback, Gharavi, Ali G., Yasar Caliskan, Avasare, Rupali S., Maddalena Marasa, Ali G. Gharavi, Yifu Li, Pietro A. Canetta, Li, Yifu, Caliskan, Yaşar Kerem, Canetta, Pietro A., Marasa, Maddalena, Bomback, Andrew S.   +17 more
core   +1 more source

Histopathological patterns and clinical variability in pediatric acute proliferative glomerulonephritis: report of four cases

Zdorovʹe Rebenka
Background. IF-negative acute proliferative glomerulonephritis (APIGN) represents a significant diagnostic pitfall, particularly when complement levels are normal and serological markers are inconclusive.
Tiffany Wongsodiharjo, Anny Setijo Rahaju, Agus Budiarto, Risky Vitria Prasetyo, Ninik Asmaningsih, Muhammad Riza Kurniawan   +5 more
doaj   +1 more source

Monoclonal gammopathy-associated C3 glomerulonephritis secondary to follicular lymphoma: a case report

Frontiers in Immunology
C3 glomerulopathy encompasses a group of glomerular diseases characterized by the predominant deposition of complement component C3 on kidney biopsy without significant immunoglobulin staining.
Wenjing Cai, Wenjing Cai, Hanguo Guo, Minghui Zhang, Huaban Liang, Huaban Liang, Xinling Liang, Xinling Liang, Yihan Wang, Qingying Shi, Zhiming Ye, Zhiming Ye, Zhilian Li, Zhilian Li   +13 more
doaj   +1 more source