Results 61 to 70 of about 162,041 (218)
Tres casos de gammapatía monoclonal de significado renal postrasplante renal: nefropatía c3 de novo
Nefrología, 2019 Resumen: La gammapatía monoclonal de significado renal incluye todas las enfermedades renales causadas por una inmunoglobulina monoclonal secretada por un clon de célula B no maligno. Por definición, los pacientes con gammapatía monoclonal de significado
Núria Serra +11 more
doaj +1 more source
C3 glomerulonephritis associated with monoclonal gammopathy of renal significance: a diagnostic and therapeutic challenge [PDF]
Brazilian Journal of NephrologyC3 glomerulopathy represents a heterogeneous group of glomerulopathies characterized by hyperactivity of the alternative complement pathway. Although the pathophysiology is incompletely understood, an association between this disease and monoclonal ...
Bárbara Beirão +5 more
doaj +1 more source
Diverse Clinical Presentations of C3 Dominant Glomerulonephritis
Frontiers in Medicine, 2020 C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic immune complex membranoproliferative glomerulonephritis (iMPGN).
Ramy M. Hanna +13 more
doaj +1 more source
Clinical Journal of the American Society of Nephrology, 2014 Summary Background and objectives The term C3 glomerulopathy describes renal disorders characterized by the presence of glomerular deposits composed of C3 in the absence of significant amounts of Ig. On the basis of electron microscopy appearance, subsets of C3 glomerulopathy include dense deposit disease (DDD) and C3
Nicholas R, Medjeral-Thomas +14 more
openaire +2 more sources
C3 Glomerulopathy With Concurrent Thrombotic Microangiopathy: Clinical and Immunological Features
, 2023 International audienceKey Points We evidenced terminal pathway activation (C5b-9 deposits) in most of the glomeruli on kidney biopsy of C3 glomerulopathy. The amount of C5b-9 deposits correlated with disease prognosis in C3 glomerulopathy.
Rabant, Marion +41 more
core +1 more source
Kidney International Reports, 2019 Introduction: Transplant glomerulopathy (TG) becomes increasingly prevalent in kidney transplant recipients over time, and it is strongly associated with allograft failure.
Sarah E. Panzer +5 more
doaj +1 more source
A clinical approach to children with C3 glomerulopathy [PDF]
Pediatric Nephrology, 2021 C3 glomerulopathy is a relatively new clinical entity that represents a challenge both to diagnose and to treat. As new therapeutic agents that act as complement inhibitors become available, many with an oral formulation, a better understanding of this disease and of the underlying complement dysregulation driving it has become increasingly useful to ...
Marina Vivarelli +4 more
openaire +3 more sources
Kidney International, 2017 In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement plays a primary role in disease pathogenesis. Herein we report the outcome of a 2015 Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference where
T. Goodship +54 more
semanticscholar +1 more source
C3 glomerulopathy and current dilemmas [PDF]
Clinical and Experimental Nephrology, 2016 C3 glomerulopathy (C3G) is a recently identified disease entity caused by dysregulation of the alternative complement pathway, and dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are its components. Because laboratory detection of complement dysregulation is still uncommon in practice, "dominant C3 deposition by two orders greater than ...
Naoko Ito, Ryuji Ohashi, Michio Nagata
openaire +2 more sources
, 2018 <p>C3 glomerulopathy (C3G) encompasses a group of severe renal diseases characterized by “dominant C3” deposition in the renal glomerulus. Patients typically present as nephritic nephrotics, with hematuria, hypertension, heavy proteinuria and edema.
Xue Xiao +5 more
openaire +3 more sources