Results 51 to 60 of about 6,839 (215)

C3 glomerulopathies: dense deposit disease and C3 glomerulonephritis

open access: yesFrontiers in Medicine, 2023
Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are types of membranoproliferative glomerulonephritis classified as C3 glomerulopathies. These conditions are characterized by an increased number of intraglomerular cells and diffuse thickening of the glomerular capillary walls, along with the deposition of C3 and minimal or absent ...
Claudio Ponticelli   +4 more
openaire   +3 more sources

Acquired partial lipodystrophy and C3 glomerulopathy: Dysregulation of the complement system as a common mechanism

open access: yesNefrología (English Edition), 2018
The activation of the alternative pathway of the complement is involved in the development of several renal diseases, such as atypical haemolytic uraemic syndrome and C3 glomerulopathy. In C3 glomerulopathy, a high percentage of patients have circulating
Fernando Corvillo   +1 more
doaj   +1 more source

Factor B Inhibition with Iptacopan in Recurrent C3 Glomerulopathy Following Kidney Transplant: A Report of Two Cases

open access: yesKidney Medicine
C3 glomerulopathy is a rare disease caused by fluid phase dysregulation of the alternative complement pathway. Currently, treatment depends on clinical and histological severity and includes nephroprotection, unspecific immunosuppression, and terminal ...
Víctor J. Escudero-Saiz   +21 more
doaj   +1 more source

Lipodistrofia parcial adquirida y glomerulopatía C3: la desregulación del sistema del complemento como mecanismo común

open access: yesNefrología, 2018
Resumen: La activación de la vía alternativa del complemento interviene en el desarrollo de varias enfermedades renales, como el síndrome hemolítico urémico atípico o la glomerulopatía C3.
Fernando Corvillo   +1 more
doaj   +1 more source

Effectiveness of Cyclosporine in a 10-year-old Girl with C3 Glomerulopathy [PDF]

open access: yesChildhood Kidney Diseases, 2017
C3 glomerulopathy (C3G) is a recently defined pathological entity characterized by C3 accumulation with absent or scant immunoglobulin deposition, leading to variable glomerular inflammation.
Kyung Mi Jang, Yong Hoon Park
doaj   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham   +4 more
wiley   +1 more source

Treatment options for C3 glomerulopathy [PDF]

open access: yesCurrent Opinion in Nephrology and Hypertension, 2013
The purpose of this review is to discuss emerging nomenclature, review the salient clinicopathological features and describe the therapeutic options available for the treatment of C3 glomerulopathy (C3G).C3G is minimally responsive to traditional immune suppression and randomized controlled trials to support therapy are absent.
Carla M, Nester, Richard J, Smith
openaire   +2 more sources

Glomerular damage as a predictor of renal allograft loss [PDF]

open access: yes, 2010
Interstitial fibrosis and tubular atrophy (IF/TA) are the most common cause of renal graft failure. Chronic transplant glomerulopathy (CTG) is present in approximately 1.5-3.0% of all renal grafts.
Araújo, Sergio   +6 more
core   +3 more sources

Evaluation of the children with C3 glomerulopathy

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2020
C3 glomerulopathy (C3G) is a clinical spectrum that presents with a variety of symptoms, ranging from a mild disease with asymptomatic microhematuria and/or proteinuria to severe disease with nephritic or nephrotic syndrome and renal impairment.
Ayse Seda Pinarbasi   +5 more
doaj   +1 more source

Adventitial Niches, Complement and Inflammation in Pulmonary Vascular Disease: Current Status and Future Directions

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Local complement production by pulmonary artery adventitial fibroblasts, activated intracellularly by CFD and CFB and extracellularly by GZMK+ CD8 T cells, and its secretion in soluble form and within EVs promotes macrophage and T cell chemotaxis and activation.
Hui Zhang   +9 more
wiley   +1 more source

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