Results 41 to 50 of about 162,041 (218)

C3 glomerulopathy is highly prevalent in French Polynesia [PDF]

Journal of Translational Autoimmunity
Objective: To compare the natural history of C3 glomerulopathy (C3G) to acute post-infectious glomerulonephritis (APIGN) in a cohort of patients with a relative homogeneity of environment conditions and genetic background.
Nelly Candela, Nicolas Benichou, Mathilde Lefebvre, Lorraine Gueguen, Paula Vieira-Martins, Carine El Sissy, Hervé Sartelet, Pascale Testevuide, Ronan Delaval, Stanislas Faguer   +9 more
doaj   +2 more sources

Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis. [PDF]

Kidney Int Rep
Introduction Approximately 50% of patients with C3 glomerulopathy (C3G) and primary immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) reach kidney failure 10 years after diagnosis.
Halfon M, Taffé P, Bucher C, Haidar F, Huynh-do U, Mani LY, Schachtner T, Wehmeier C, Venetz JP, Pascual M, Fakhouri F, Golshayan D, Swiss Transplant Cohort Study.   +12 more
europepmc   +2 more sources

Developing Therapies for C3 Glomerulopathy: Report of the Kidney Health Initiative C3 Glomerulopathy Trial Endpoints Work Group. [PDF]

Clin J Am Soc Nephrol
Randomized clinical trials are underway to evaluate the efficacy of novel agents targeting the alternative complement pathway in patients with C3 glomerulopathy (C3G), a rare glomerular disease. The Kidney Health Initiative convened a panel of experts in
Nester C, Decker DA, Meier M, Aslam S, Bomback AS, Caravaca-Fontán F, Cook TH, Feldman DL, Fremeaux-Bacchi V, Gale DP, Gooch A, Johnson S, Licht C, Mathur M, Pickering MC, Praga M, Remuzzi G, Selvarajah V, Smith RJ, Tabriziani H, van de Kar N, Wang Y, Wong E, Mistry K, Lim M, Portillo C, Balogun S, Trachtman H, Thompson A.   +28 more
europepmc   +2 more sources

C3 glomerulopathy disease

Cumhuriyet Medical Journal, 2018
C3 glomerulopati (C3G), kompleman aktivasyonunun anormal kontrolü ile oluşan bir grup böbrek hastalığını kapsayan yakın zamanda tanımlanmış bir hastalıktır.
Ferhan Candan³, Can Huzmeli¹, Mehmet Hadi Akkus²   +2 more
core   +3 more sources

C3 Glomerulopathy and related disorders in children [PDF]

, 2021
Background and objectives: Membranoproliferative Glomerulonephritis (MPGN) and C3 Glomerulopathy are rare and overlapping disorders associated with dysregulation of the alternative complement pathway.
Gale, Daniel P., Martin Christian, Heather Maxwell, Marks, Stephen D., Marks, Stephen, H. Terence Cook, Svetlana Hakobyan, Daniel P. Gale, Harris, Claire L., Paul McAlinden, Harris, Claire, Edwin K.S. Wong, Cooke, Katie, Sally A. Johnson, Hakobyan, Svetlana, Isabel Y. Pappworth, Goodship, Timothy, Roger Malcomson, Marchbank, Kevin, Hannah Lomax-Browne, Sophie Ward, Katie Cooke, Richardson, Grant, Amy-Claire McLoughlin, Grant Richardson, Cook, H. Terence, Maxwell, Heather, Wong, Edwin, Wilson, Valerie, Johnson, Sally, Ward, Sophie, Claire L. Harris, Valerie Wilson, Lomax-Browne, Hannah, Stephen D. Marks, Kevin J. Marchbank, Pickering, Matthew, McAlinden, Paul, Gale, Daniel, Denton, Harriet, Harriet Denton, B. Paul Morgan, David Kavanagh, Marchbank, Kevin J., Morgan, B. Paul, Matthew C. Pickering, Christian, Martin, McLoughlin, Amy-Claire, Pappworth, Isabel, Pickering, Matthew C., Malcomson, Roger, Timothy H.J. Goodship, Johnson, Sally A., Kavanagh, David, Goodship, Timothy H.J., Wong, Edwin K.S., Pappworth, Isabel Y.   +56 more
core   +2 more sources

C3 glomerulopathy

Cleveland Clinic Journal of Medicine, 2023
C3 glomerulopathy (C3G) is a rare kidney disease that causes kidney dysfunction as a result of dysregulation of the complement system alternate pathway (AP). C3G encompasses 2 separate disorders, C3 glomerulonephritis and dense deposit disease. The presentation and natural history is variable and kidney biopsy is needed to confirm the diagnosis.
Ali, Mehdi, Jonathan J, Taliercio
openaire   +2 more sources

Complement Terminal Pathway Activation and Intrarenal Immune Response in C3 Glomerulopathy

Journal of the American Society of Nephrology
International audienceBackground : C3 glomerulopathy is a rare disease resulting from an overactivation of the complement alternative pathway. Although there is also evidence of terminal pathway activation, its occurrence and consequences on the disease ...
Duval, Anna, Rabant, Marion, Karras, Alexandre, Boyer, Olivia, Gilmore, Alyssa, Meuleman, Marie-Sophie, Pickering, Matthew, Audard, Vincent, Bridoux, Frank, Hogan, Julien, Petitprez, Florent, Thervet, Eric, Gnemmi, Vivianne, Chauvet, Sophie, Le Quintrec, Moglie, Buob, David, Artero, Mikel Rezola, Servais, Aude, Goujon, Jean-Michel, Frémeaux Bacchi, Véronique, Duong van Huyen, Jean-Paul, Moktefi, Anissa, Roumenina, Lubka, Provôt, François, Eloudzeri, Maeva, Grünenwald, Anne, Boffa, Jean-Jacques   +26 more
core   +2 more sources

Characterization of C3 in C3 glomerulopathy [PDF]

Nephrology Dialysis Transplantation, 2016
Abstract Background: C3 glomerulopathy (C3G) is caused by overactivity of the alternative pathway of complement that results in bright glomerular C3 staining with minimal or no deposition of immunoglobulins on immunofluorescence microscopy.
Sanjeev, Sethi, Julie A, Vrana, Fernando C, Fervenza, Jason D, Theis, Amit, Sethi, Paul J, Kurtin, Yuzhou, Zhang, Richard J H, Smith   +7 more
openaire   +2 more sources

Clinical Images: Anti‐MDA5 dermatomyositis with rapidly progressive interstitial lung disease presenting with rapidly progressive glomerulonephritis due to C3 glomerulopathy [PDF]

ACR Open Rheumatol
ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Lebhar J, Kellogg B, Herndon S, Sims C, Maheswaranathan M, Howell D, Optican R.   +6 more
europepmc   +2 more sources

Overview of C3 Glomerulopathy [PDF]

Frontiers in Pediatrics, 2016
C3 glomerulopathy is an umbrella term, which includes several rare forms of glomerulonephritis (GN) with underlying defects in the alternate complement cascade. A common histological feature noted in all these GN is dominant C3 deposition in the glomerulus.
Master Sankar Raj, Vimal, Gordillo, Roberto, Chand, Deepa H.   +2 more
openaire   +2 more sources