Results 31 to 40 of about 4,362 (171)
Diverse Clinical Presentations of C3 Dominant Glomerulonephritis
Frontiers in Medicine, 2020 C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic immune complex membranoproliferative glomerulonephritis (iMPGN).
Ramy M. Hanna +13 more
doaj +1 more source
Recent insights into C3 glomerulopathy [PDF]
Nephrology Dialysis Transplantation, 2013 'C3 glomerulopathy' is a recent disease classification comprising several rare types of glomerulonephritis (GN), including dense deposit disease (DDD), C3 glomerulonephritis (C3GN) and CFHR5 nephropathy. These disorders share the key histological feature of isolated complement C3 deposits in the glomerulus. A common aetiology involving dysregulation of
Barbour, TD, Pickering, MC, Cook, HT
openaire +3 more sources
Kidney International Reports, 2019 Introduction: Transplant glomerulopathy (TG) becomes increasingly prevalent in kidney transplant recipients over time, and it is strongly associated with allograft failure.
Sarah E. Panzer +5 more
doaj +1 more source
Clinical Journal of the American Society of Nephrology, 2014 Summary Background and objectives The term C3 glomerulopathy describes renal disorders characterized by the presence of glomerular deposits composed of C3 in the absence of significant amounts of Ig. On the basis of electron microscopy appearance, subsets of C3 glomerulopathy include dense deposit disease (DDD) and C3
Nicholas R, Medjeral-Thomas +14 more
openaire +2 more sources
, 2018 <p>C3 glomerulopathy (C3G) encompasses a group of severe renal diseases characterized by “dominant C3” deposition in the renal glomerulus. Patients typically present as nephritic nephrotics, with hematuria, hypertension, heavy proteinuria and edema.
Xue Xiao +5 more
openaire +3 more sources
C3 glomerulopathy in cystic fibrosis: a case report
BMC Nephrology, 2018 Background C3 glomerulonephritis is a rare glomerulopathy characterized at renal biopsy by C3 deposition, alone or with scanty immunoglobulins, as well as by an electron-dense material in mesangium, subendothelial and subepithelial space.
Domenico Santoro +9 more
doaj +1 more source
A clinical approach to children with C3 glomerulopathy [PDF]
Pediatric Nephrology, 2021 C3 glomerulopathy is a relatively new clinical entity that represents a challenge both to diagnose and to treat. As new therapeutic agents that act as complement inhibitors become available, many with an oral formulation, a better understanding of this disease and of the underlying complement dysregulation driving it has become increasingly useful to ...
Marina Vivarelli +4 more
openaire +3 more sources
Nefrología (English Edition), 2018 The activation of the alternative pathway of the complement is involved in the development of several renal diseases, such as atypical haemolytic uraemic syndrome and C3 glomerulopathy. In C3 glomerulopathy, a high percentage of patients have circulating
Fernando Corvillo +1 more
doaj +1 more source
C3 glomerulopathy and current dilemmas [PDF]
Clinical and Experimental Nephrology, 2016 C3 glomerulopathy (C3G) is a recently identified disease entity caused by dysregulation of the alternative complement pathway, and dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are its components. Because laboratory detection of complement dysregulation is still uncommon in practice, "dominant C3 deposition by two orders greater than ...
Naoko Ito, Ryuji Ohashi, Michio Nagata
openaire +2 more sources
Kidney MedicineC3 glomerulopathy is a rare disease caused by fluid phase dysregulation of the alternative complement pathway. Currently, treatment depends on clinical and histological severity and includes nephroprotection, unspecific immunosuppression, and terminal ...
Víctor J. Escudero-Saiz +21 more
doaj +1 more source