Results 71 to 80 of about 6,839 (215)
Circulating Complement Levels and C3 Glomerulopathy [PDF]
Clinical Journal of the American Society of Nephrology, 2014 The complement system is an essential part of innate immunity acting as a first-line defense against infection and provides an interface between innate and adaptive immunity ([1][1],[2][2]). It consists of a network of soluble (fluid phase) and cell membrane proteins (solid phase).
Fernando C, Fervenza, Sanjeev, Sethi
openaire +2 more sources
Kartagener Syndrome With Focal Segmental Glomerulosclerosis [PDF]
, 2013 Primary ciliary dyskinesia is characterized by congenital impairment of mucociliary clearance. Kartagener syndrome (KS) is a clinical variant of primary ciliary dyskinesia which is involved in situs inversus associated with chronic respiratory infections.
Doroushi, Behzad +2 more
core
Treatment of steroid-resistant pediatric nephrotic syndrome [PDF]
, 2011 Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the ...
Hee Gyung Kang
core +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley +1 more source
C3 Glomerulonephritis: A Rare Etiology of the Pulmonary Renal Syndrome
Kidney Medicine, 2019 C3 Glomerulopathy is a rare form of kidney disease due to dysregulation of the alternative complement pathway. We report a case of a college-aged woman with C3 glomerulonephritis (C3GN), presenting with the unexpected extrarenal manifestation of ...
Shane A. Bobart +2 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley +1 more source
BMC Ophthalmology, 2017 Background To describe the optical coherence tomography angiograhy (OCTA) of drusenoid pigment epithelial detachments (PEDs) in a woman affected by Complement 3 (C3) glomerulopathy, which represents a spectrum of glomerular diseases characterized on ...
Valeria Kheir +5 more
doaj +1 more source
Recent Progress in Double Filtration Plasmapheresis
Hemodialysis International, Volume 30, Issue 1, Page 18-25, January 2026.ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li +3 more
wiley +1 more source
C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases
Frontiers in Immunology, 2019 C3 glomerulopathy (C3G) is a severe kidney disease, which is caused by defective regulation of the alternative complement pathway. Disease pathogenesis is heterogeneous and is caused by both autoimmune and genetic factors.
Fei Zhao +13 more
doaj +1 more source
Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.The paradigm of renal involvement in HIV patients has changed in recent years, from HIV‐associated nephropathy to nephroangiosclerosis, due to the increased survival of these patients and their comorbidities. Some of these are leishmaniasis and hepatitis C and their treatments, especially direct‐acting antivirals, which may induce reconstitution of the
María Adoración Martín Gómez +6 more
wiley +1 more source