Results 211 to 220 of about 56,153 (264)

The Role of Complement and CD4 T Cells in Preeclampsia and Offspring Neurodevelopment. [PDF]

Curr Opin Physiol
Regal JF, O'Kane CA, Scroggins SM.
europepmc   +1 more source

Complement C3a Suppresses Spinal Cord Neural Stem Cell Activation by Inhibiting UCHL1 via the NF-κB p65/Nrf2 Pathway. [PDF]

Neurosci Bull
Ding L, Li X, Guo Y, Zhou FQ, Deng DYB.
europepmc   +1 more source

Identification of functional genetic components modulating toxicity response to PFOS using genome-wide CRISPR screens in HepG2/C3A cells. [PDF]

Arch Toxicol
Kim C, Tagmount A, Zhu Z, Wilson F, Li D, Ostrov DA, Brad Barbazuk W, Bacher R, Vulpe CD.   +8 more
europepmc   +1 more source

The Role of Complement Activation in Diabetic Nephropathy: Current Insights and Future Directions. [PDF]

J Clin Med
Kotsalas N, Fouza A, Daoudaki M.
europepmc   +1 more source

Complement response to burn injury: systematic review and meta-analysis of patient and animal studies. [PDF]

Front Immunol
Mulder PPG, van Hooren M, Bumbuc RV, Hooijmans CR, Korkmaz HI, Boekema BKHL.   +5 more
europepmc   +1 more source

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Synthetic C3a analogs as specific inhibitors of C3a activity

Immunopharmacology, 1981
Various C3a-related C-terminal synthetic oligopeptides were investigated for their ability to induce a release of serotonin from guinea pig platelets. The results confirm earlier findings that expression of biological C3a activity requires the four to five C-terminal amino acids of the C3a primary structure and underlines the essential role of the C ...
U Hadding, D Bitter-Suermann
exaly   +3 more sources

Anaphylatoxin C3a but not C3a(desArg) is a chemotaxin for the mouse macrophage cell line J774 [PDF]

European Journal of Immunology, 1998
Varying results have been published regarding the functional reactivity of different cell types, including human monocytes, to the anaphylatoxin C3a and its degradation product C3a(desArg). To further delineate the functions of C3a and C3a(desArg) on this cell type we used the murine macrophage (Mø) cell line J774A.1 which is known to respond to the ...
Jörg Zwirner, Thomas Werfel, O Götze   +2 more
exaly   +3 more sources

C3a(desArg) does not bind to and signal through the human C3a receptor

Immunology Letters, 1999
Contradictory results have been published in the past regarding the functional responses of different cell types to the anaphylatoxin C3a and its natural catabolite C3a(desArg). To elucidate the interaction of the C3a receptor (C3aR) with its ligand(s) we studied the binding of human recombinant C3a (rC3a) and rC3a(desArg) to RBL-2H3 transfectants ...
O Götze, Thomas Werfel, Jörg Zwirner   +2 more
exaly   +3 more sources