Results 51 to 60 of about 6,868 (161)
Veterinary Dermatology, Volume 37, Issue 2, Page 236-246, April 2026.Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon +2 more
wiley +1 more source
Complement System and C4d expression in cases of Membranous nephropathy
Brazilian Journal of NephrologyIntroduction: Membranous nephropathy (MN) is one of the major causes of nephrotic syndrome. The complement system plays a key role in the pathophysiology of MN.
Fabiano Bichuette Custódio +4 more
doaj +1 more source
Veterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes +8 more
wiley +1 more source
Focal peritubular capillary C4d deposition in acute rejection [PDF]
Nephrology Dialysis Transplantation, 2006 Diffuse peritubular capillary (PTC) C4d deposition has been shown to be associated with relatively poor graft outcome. The significance of focal PTC C4d staining in the early post-transplant period is uncertain.Sixty-five biopsies from 53 patients with acute rejection were graded (Banff '97 criteria), stained for C4d, monocytes and T cells, and divided
Alexander B, Magil, Kathryn J, Tinckam
openaire +2 more sources
Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source
Veterinary Dermatology, Volume 37, Issue 2, Page 247-256, April 2026.ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Evi I. Sofou +4 more
wiley +1 more source
Clinical relevance of preformed C4d-fixing and non-C4d-fixing HLA single antigen reactivity in renal allograft recipients [PDF]
Transplant International, 2009 Donor-specific alloantibodies (DSA), especially those fixing complement, may pose a particular immunologic risk to transplant recipients. To assess the clinical impact of C4d- or non-C4d-fixing (IgG) HLA sensitization, pretransplant sera obtained from 338 kidney allograft recipients prescreened by FlowPRA were retrospectively evaluated by Luminex ...
Markus, Wahrmann +6 more
openaire +2 more sources
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?
Arthritis &Rheumatology, Volume 78, Issue 3, Page 548-557, March 2026.Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin +11 more
wiley +1 more source
Nefrología, 2017 Objetivos: 1) Identificar las variables que se asocian con los niveles urinarios de MBL, C4d y C5b-9 en enfermos con nefropatía IgA idiopática. 2) Analizar si los niveles urinarios de MBL o C4d son útiles para identificar la presencia de depósitos ...
Alfons Segarra-Medrano +6 more
doaj +1 more source
Dense deposit disease involving C3 and C4d Deposits
Indian Journal of Nephrology, 2018 Dense deposit disease (DDD), earlier called Type II membranoproliferative glomerulonephritis is distinct disease having frequent relapses reaching end-stage kidney disease by 10-year in up to 50%-60% of cases and high recurrence rate in the allograft. The term DDD is derived from its distinctive ribbon-like osmiophilic deposits in the lamina densa of ...
Vankalakunti, M. +6 more
openaire +2 more sources