Results 131 to 140 of about 53,790 (237)
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
ABSTRACT Examining the extent to which measurements of rotation matrices are close to each other is challenging due measurement noise. To overcome this, data is typically smoothed, and the Riemannian and Euclidean metrics are applied. However, if rotation matrices are not directly measured and are instead formed by eigenvectors of measured symmetric ...
P. D. Ledger +2 more
wiley +1 more source
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu +5 more
wiley +1 more source
C5a Receptor Oligomerization [PDF]
Desiree H. Floyd +5 more
openaire +3 more sources
ABSTRACT IgA nephropathy is a progressive glomerular disease with a variable clinical course and a substantial risk of progression to end‐stage kidney failure. While proteinuria has long been the central therapeutic target, insights into disease pathogenesis indicate that haematuria should also guide treatment decisions. Based on the pathophysiology of
Yusuke Suzuki
wiley +1 more source
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka +3 more
wiley +1 more source
Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]
A.L. Manson +12 more
core +1 more source
The novel B-cell epitope peptide vaccine, MAX449, exhibits significant anti-tumor efficacy and enhances the therapeutic effects of PD-1 antibodies on tumors by modulating the activity of PMN-MDSCs. [PDF]
Yang H +14 more
europepmc +1 more source

