Results 171 to 180 of about 2,358,049 (278)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, Volume 59, Issue 2, February 2026.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

Principles for Optimal Drug Selection in IgA Nephropathy—Time for Integrating Pathogenesis and Clinical Markers to Guide Therapy

Nephrology, Volume 31, Issue 2, February 2026.
ABSTRACT IgA nephropathy is a progressive glomerular disease with a variable clinical course and a substantial risk of progression to end‐stage kidney failure. While proteinuria has long been the central therapeutic target, insights into disease pathogenesis indicate that haematuria should also guide treatment decisions. Based on the pathophysiology of
Yusuke Suzuki
wiley   +1 more source

Author Correction: Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism. [PDF]

Commun Biol, 2021
Dumitru AC, Deepak RNVK, Liu H, Koehler M, Zhang C, Fan H, Alsteens D.   +6 more
europepmc   +1 more source

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo

Veterinary Dermatology, Volume 37, Issue 1, Page 140-147, February 2026.
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka, Elisabeta Samuel (Badulescu), Manolis K. Chatzis, Manolis N. Saridomichelakis   +3 more
wiley   +1 more source

Immunohistochemical identification of complement peptide C5a receptor 1 (C5aR1) in non-neoplastic and neoplastic human tissues. [PDF]

PLoS One, 2021
Nürge B, Schulz AL, Kaemmerer D, Sänger J, Evert K, Schulz S, Lupp A.   +6 more
europepmc   +1 more source

Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]

, 2015
A.L. Manson, Arend, Gekowski, H.J. Longhurst, Haeffner-Cavaillon, J.D. Cavenagh, M.S. Buckland, Nashan, Okusawa, P.F.K. Yong, Rybojad, S. Grigoriadou, Schindler   +12 more
core   +1 more source

Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock. [PDF]

Sci Rep, 2021
Chakraborty S, Winkelmann VE, Braumüller S, Palmer A, Schultze A, Klohs B, Ignatius A, Vater A, Fauler M, Frick M, Huber-Lang M.   +10 more
europepmc   +1 more source

Complement 5 (C5); C5a; C5a receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex–induced arthritis

Science immunology, 2017
Y. Miyabe, C. Miyabe, T. Murooka, Edward Y. Kim, G. Newton, Nancy D. Kim, B. Haribabu, F. Luscinskas, T. Mempel, A. Luster   +9 more
semanticscholar   +1 more source

Structural insights into ligand-recognition, activation, and signaling-bias at the complement C5a receptor, C5aR1

, 2023
Saha S, Maharana J, Yadav MK, Sarma P, Singh V, Mohapatra S, Soni C, Saha S, Mishra S, Ganguly M, Chami M, Banerjee R, Shukla AK.   +12 more
europepmc   +1 more source