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Atypical complement receptor C5aR2 transports C5a to initiate neutrophil adhesion and inflammation
Science Immunology, 2019C5aR2 transports C5a into the blood vessel lumen to initiate neutrophil arrest in a murine model of arthritis.
Yoshishige Miyabe +4 more
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Differential effects of anaphylatoxin C5a on antigen presenting cells, roles for C5aR1 and C5aR2
Immunology Letters, 2019The anaphylatoxin C5a is well-known for its role as chemoattractant and contributes to immune cell recruitment into inflamed tissue and local inflammation. C5a has recently been implicated in modulation of antigen presenting cell function, such as macrophages and dendritic cells, which are pivotal for T cell activation and final T cell effector ...
Zaal, A. +2 more
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The complement receptor C5aR2 is protective in hypertensive end organ damage
Molecular Immunology, 2018Marlies Bode +5 more
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Investigating the immunopharmacology of the complement C5a receptors, C5aR1 and C5aR2
2021openaire +2 more sources
The Importance of C5aR2 in Neutrophil Function and Its Impact on Neutrophil-mediated Diseases
Journal of Cellular Immunology, 2022openaire +1 more source
Independent role of C5aR1 and C5aR2 during acute Toxoplasma gondii infection
Molecular Immunology, 2017Fabian T. Mey +4 more
openaire +1 more source