Results 1 to 10 of about 92,246 (207)

Cancer Cachexia Prevalence Is Underestimated in Medical Records of Patients in a Regional Tertiary Hospital [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Widespread lack of awareness and limited real‐world prevalence evidence have impeded cachexia care and research. We hypothesized that healthcare professionals may identify the term cachexia, leading to International Classification of Diseases (
Yann Colardelle, Melanie Daligault, Julien Grosjean, Stefan J. Darmoni, Badisse Dahamna, Richard B. Weiskopf, Vickie E. Baracos   +6 more
doaj   +2 more sources

Identification of circulating plasma ceramides as a potential sexually dimorphic biomarker of pancreatic cancer‐induced cachexia

JCSM Rapid Communications, 2022
Background Cancer patients who exhibit cachexia lose weight and have low treatment tolerance and poor outcomes compared with cancer patients without weight loss.
Jeffery M. Chakedis, Mary E. Dillhoff, Carl R. Schmidt, Priyani V. Rajasekera, David C. Evans, Terence M. Williams, Denis C. Guttridge, Erin E. Talbert   +7 more
doaj   +1 more source

Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy.
Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene   +9 more
doaj   +1 more source

Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes.
Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley A. Haynie, Jacob L. Brown, John William Deaver, Francielly Morena Da Silva, Lisa T. Jansen, David E. Lee, Michael P. Wiggs, Tyrone A. Washington, Nicholas P. Greene   +10 more
doaj   +1 more source

Screening Assessment and Therapy Intervention of Cancer Cachexia in Adult Patients——Based on the Interpretation of Cancer Cachexia in Adult Patients: ESMO Clinical Practice Guidelines [PDF]

Zhongguo quanke yixue, 2023
Cancer cachexia is a cancer-related, multi-factorial, irreversible clinical syndrome characterized by progressive nutritional consumption, which greatly reduces the survival expectation and quality of life of cancer patient.
WANG Rui, WANG Xiaomei, PENG Guoqing, YU Huan, WANG Sihan, XIA Jin
doaj   +1 more source

Cancer cachexia [PDF]

QJM: An International Journal of Medicine, 2005
Cancer cachexia is a severe debilitating disorder for which there are currently few therapeutic options. It is driven by the release of pro-inflammatory cytokines and cachectic factors by both host and tumour. Over the past few years, basic science advances have begun to reveal the breadth and complexity of the immunological mechanisms involved, and in
J N, Gordon, S R, Green, P M, Goggin
openaire   +2 more sources

Cancer cachexia

Journal of Parenteral and Enteral Nutrition, 1988
Cancer cachexia describes a syndrome of progressive weight loss, anorexia, and persistent erosion of host body cell mass in response to a malignant growth. Although often associated with preterminal patients bearing disseminated disease, cachexia may be present in the early stages of tumor growth before any signs or symptoms of malignancy. A decline in
K A, Kern, J A, Norton
openaire   +5 more sources

Heme metabolism genes Downregulated in COPD Cachexia. [PDF]

, 2020
IntroductionCachexia contributes to increased mortality and reduced quality of life in Chronic Obstructive Pulmonary Disease (COPD) and may be associated with underlying gene expression changes.
Agusti, Alvar, Arora, Itika, Bhatt, Surya P, Casaburi, Richard, Castaldi, Peter J, Dransfield, Mark T, Hersh, Craig P, Kumar, Preeti L, Lee, Sool, Lomas, David A, McDonald, Merry-Lynn N, Morrow, Jarrett D, Parker, Margaret M, Rennard, Stephen I, Silverman, Edwin K, Tal-Singer, Ruth, Thannickal, Victor J, Tiwari, Hemant K, Washko, George, Wells, J Michael, Wilson, Ava C, Wouters, Emiel FM   +21 more
core   +3 more sources

Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]

, 2014
Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar, Andrew Eugene Hendifar, Carlyn Rose Tan, Laith eJamil, Nick eNissen, Patrick eYaffee, Richard eTuli, Simon eLo, Stephen J Pandol   +8 more
core   +2 more sources

Cachexia in Cancer Patients: Systematic Literature Review

Asian Journal of Oncology, 2020
Introduction Cachexia in cancer patients, especially in advanced stage, is recently known as an emerging problem. Cachexia occurs in about half of all patients with neoplastic disease.
Timotius I. Hariyanto, Andree Kurniawan
doaj   +1 more source