Results 1 to 10 of about 110,913 (348)

Management of Cancer Cachexia: ASCO Guideline

open access: yesJournal of Clinical Oncology, 2020
PURPOSE To provide evidence-based guidance on the clinical management of cancer cachexia in adult patients with advanced cancer. METHODS A systematic review of the literature collected evidence regarding nutritional, pharmacologic, and other ...
Eric J Roeland   +2 more
exaly   +2 more sources

The interplay of immunology and cachexia in infection and cancer

open access: yesNature Reviews Immunology, 2021
Diverse inflammatory diseases, infections and malignancies are associated with wasting syndromes. In many of these conditions, the standards for diagnosis and treatment are lacking due to our limited understanding of the causative molecular mechanisms ...
Hatoon Baazim, Laura, Andreas Bergthaler
exaly   +2 more sources

Cachexia [PDF]

open access: yesDuodecim lääketieteellinen aikakauskirja, 2020
Cachexia is a frequent syndrome in patients suffering from advanced cancer; it is characterized by anorexia, weight loss, and malnutrition, which combined with other psychic and social consequences lead to a deterioration in a patient's quality of life ...
O. Ukkola
openaire   +2 more sources

Clinical validation of AWGC-defined cachexia in gastric cancer patients: impact on body composition and quality of life [PDF]

open access: yesFrontiers in Nutrition
BackgroundThe Asian Working Group for Cachexia (AWGC) has released consensus criteria for diagnosing cachexia in Asians. Nevertheless, there is limited data regarding the application of these criteria in cancer patients.
Yan Huang   +8 more
doaj   +2 more sources

Cancer cachexia: molecular mechanisms and treatment strategies

open access: yesJournal of Hematology & Oncology, 2023
Muscle wasting is a consequence of physiological changes or a pathology characterized by increased catabolic activity that leads to progressive loss of skeletal muscle mass and strength.
Tania Setiawan   +7 more
semanticscholar   +1 more source

Identification of circulating plasma ceramides as a potential sexually dimorphic biomarker of pancreatic cancer‐induced cachexia

open access: yesJCSM Rapid Communications, 2022
Background Cancer patients who exhibit cachexia lose weight and have low treatment tolerance and poor outcomes compared with cancer patients without weight loss.
Jeffery M. Chakedis   +7 more
doaj   +1 more source

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2021

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
The Journal of Cachexia, Sarcopenia and Muscle (JCSM) aims to publish articles with relevance to wasting disorders and illnesses of the muscle in the broadest sense. In order to avoid publication of inappropriate articles and to avoid protracted disputes,
S. von Haehling   +2 more
semanticscholar   +1 more source

Screening Assessment and Therapy Intervention of Cancer Cachexia in Adult Patients——Based on the Interpretation of Cancer Cachexia in Adult Patients: ESMO Clinical Practice Guidelines [PDF]

open access: yesZhongguo quanke yixue, 2023
Cancer cachexia is a cancer-related, multi-factorial, irreversible clinical syndrome characterized by progressive nutritional consumption, which greatly reduces the survival expectation and quality of life of cancer patient.
WANG Rui, WANG Xiaomei, PENG Guoqing, YU Huan, WANG Sihan, XIA Jin
doaj   +1 more source

Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy.
Megan E. Rosa‐Caldwell   +9 more
doaj   +1 more source

Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Background Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes.
Megan E. Rosa‐Caldwell   +10 more
doaj   +1 more source

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