Results 1 to 10 of about 3,705 (137)

Characteristics and Long‐Term Outcome of Acute Ischemic Stroke in Patients With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Compared With Sporadic Small Vessel Occlusion [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often presents as acute ischemic stroke involving cerebral perforators.
Sang Hee Ha, Jae Young Park, Sung Hee Ahn, Jun Young Chang, Chong Hyun Suh, Hyunjin Kim, Jae‐Sung Lim, Dong‐Wha Kang, Sun U. Kwon, Satoshi Saito, Bum Joon Kim   +10 more
doaj   +2 more sources

More than lacunes and leukoencephalopathy: A hemorrhagic stroke in CADASIL [PDF]

Radiology Case Reports
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary small vessel disease caused by mutations in the NOTCH3 gene.
Chaimaa Jabbari, MD, Aya Laridi, MD, Ihssane Laasri, MD, Abdallah Bennasser, MD, ElMahdi Ait Belhaj, MD, Ayman El Farouki, PhD, Jamal El Fenni, PhD   +6 more
doaj   +2 more sources

Study of the NOTCH3 Gene Reveals the First CADASIL Cases in Crete and a Novel Pathogenic Variant [PDF]

Brain and Behavior
Background NOTCH3 gene variants are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Ioannis Zaganas, Ioannis Tsiverdis, Evgenia Kokosali, Ionela Litso, Minas Drakos, Irene Skoula, Alexandros Zabetakis, Lambros Mathioudakis, Vassilios Mastorodemos, Panayiotis Mitsias   +9 more
doaj   +2 more sources

Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Frontiers in Cellular Neuroscience, 2023
IntroductionCerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common genetic small vessel disease caused by variants in the NOTCH3 gene.
Wenjun Zhang, Xiangjun Zhao, Xuewei Qi, Susan J. Kimber, Nigel M. Hooper, Nigel M. Hooper, Tao Wang, Tao Wang, Tao Wang   +8 more
doaj   +1 more source

Neuroimaging Characteristics of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) in Korean Based on Jeju Cohort: A Pictorial Essay

Journal of the Korean Society of Radiology, 2023
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary small artery vasculopathy caused by mutations in the NOTCH3 gene on chromosome 19.
Yeh Rin Suh, Ho Kyu Lee, Kyeong Ho Jung, Jung Seok Lee, Jay Chol Choi   +4 more
doaj   +1 more source

Headache and NOTCH3 Gene Variants in Patients with CADASIL

Neurology International, 2023
Autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited vascular disease characterized by recurrent strokes, cognitive impairment, psychiatric symptoms, apathy, and migraine.
Oliwia Szymanowicz, Izabela Korczowska-Łącka, Bartosz Słowikowski, Małgorzata Wiszniewska, Ada Piotrowska, Ulyana Goutor, Paweł P. Jagodziński, Wojciech Kozubski, Jolanta Dorszewska   +8 more
doaj   +1 more source

Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease

Molecular Brain, 2020
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is one of the most common forms of hereditary cerebral small vessel diseases and is caused by mutations in NOTCH3.
Yumi Yamamoto, Katsutoshi Kojima, Daisuke Taura, Masakatsu Sone, Kazuo Washida, Naohiro Egawa, Takayuki Kondo, Eiko N. Minakawa, Kayoko Tsukita, Takako Enami, Hidekazu Tomimoto, Toshiki Mizuno, Raj N. Kalaria, Nobuya Inagaki, Ryosuke Takahashi, Mariko Harada-Shiba, Masafumi Ihara, Haruhisa Inoue   +17 more
doaj   +1 more source

A Nationwide Survey and Multicenter Registry-Based Database of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy in Japan

Frontiers in Aging Neuroscience, 2020
ObjectivesClinical characteristics of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) include migraine, recurrent stroke, white matter lesions, and vascular dementia.
Akihiro Shindo, Ken-ichi Tabei, Akira Taniguchi, Hiroaki Nozaki, Osamu Onodera, Akihiko Ueda, Yukio Ando, Yukio Ando, Takao Urabe, Kazumi Kimura, Kazuo Kitagawa, Haruo Hanyu, Teruyuki Hirano, Hideaki Wakita, Hidenao Fukuyama, Tatsuo Kagimura, Yoshihiro Miyamoto, Misa Takegami, Satoshi Saito, Akiko Watanabe-Hosomi, Ikuko Mizuta, Masafumi Ihara, Toshiki Mizuno, Hidekazu Tomimoto   +23 more
doaj   +1 more source

Recurrent generalized seizures as the prominent manifestation in a patient with CADASIL: a case report and literature review

BMC Neurology, 2022
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited arteriopathy typically caused by mutations in the NOTCH-3 gene. Few detailed descriptions of recurrent generalized seizures in
Liuhua Pan, Yan Chen, Shanshan Zhao
doaj   +1 more source

Incipient CADASIL [PDF]

Archives of Neurology, 2003
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the NOTCH3 gene. Knowledge of disease expression in young adult NOTCH3 mutation carriers (MCs) is limited.To characterize clinical, neuropsychological, and radiological status in NOTCH3 MCs younger than 35 years.Clinical ...
Saskia A J, Lesnik Oberstein, Rivka, van den Boom, Huub A M, Middelkoop, Michel D, Ferrari, Yvette M, Knaap, Hans C, van Houwelingen, Martijn H, Breuning, Mark A, van Buchem, Joost, Haan   +8 more
openaire   +2 more sources