Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
The atypical cadherins Fat and Dachsous (Ds) signal through the Hippo pathway to regulate growth of numerous organs, including the Drosophila wing. Here, we find that Ds-Fat signaling tunes a unique feature of cell proliferation found to control the rate
Andrew Liu +3 more
doaj +1 more source
Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells [PDF]
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related death worldwide. Current treatments are extremely disappointing.
Alaniz, Laura Daniela +8 more
core +1 more source
Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan +8 more
wiley +1 more source
Recent progress in T-cadherin (CDH13, H-cadherin) research.
T-cadherin is a unique cadherin cell adhesion molecule that is anchored to the cell surface membrane through a glycosyl phosphatidyl inositol (GPI) moiety. The cytoplasmic domain, which T-cadherin lacks, is believed to be critical for homophilic binding through interaction with submembrane cytoskeletal proteins.
Takeuchi, T., Ohtsuki, Y.
openaire +3 more sources
Prognostic impact of the loss of E-cadherin and de novo expression of N-cadherin at the invasive front of primary and recurrent oral squamous cell carcinoma [PDF]
Samer G. Hakim +7 more
openalex +1 more source
Proteolytic cleavage of cadherins: Functional role of the cleaved extracellular and cytoplasmic domains [PDF]
Dynamic regulation of cadherin mediated cell-cell adhesion is crucial for morphogenesis and tissue homeostasis. Cadherin adhesive function can be regulated by distinct proteolytic cleavage events, resulting in release of either the ectodomain or ...
Billion, Karla
core
A Peculiarly Cerebroid Convex Zygo-Dodecahedron is an Axiomatically Balanced “House of Blues”: The Circle of Fifths to the Circle of Willis to Cadherin Cadenzas [PDF]
A bilaterally symmetrical convex dodecahedron consisting of twelve quadrilateral faces is derived from the icosahedron via a process akin to Fuller’s Jitterbug Transformation.
Becker, David A.
core +2 more sources
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
El carcinoma de células renales es el cáncer renal más común en el adulto. Se describen 5 tipos histológicos principales, que, en general, muestran al microscopio óptico características que permiten diagnosticarlos.
Anay Marquetti Hernández +1 more
doaj

