Results 111 to 120 of about 65,722 (350)

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells

Stem Cell Reports, 2017
Calreticulin, a multifunctional endoplasmic reticulum resident protein, is required for TGF-β-induced epithelial-to-mesenchymal transition (EMT) and subsequent cardiomyogenesis. Using embryoid bodies (EBs) derived from calreticulin-null and wild-type (WT)
Fereshteh Karimzadeh, Michal Opas
doaj   +1 more source

Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours [PDF]

, 2022
Kristin Astrid Øystese, Olivera Casar‐Borota, Jon Berg–Johnsen, Jens Petter Berg, Jens Bollerslev   +4 more
openalex   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Expression of cell adhesion molecules in the normal and T3 blocked development of the tadpole's kidney of Bufo arenarum (Amphibian, Anuran, Bufonidae)

Brazilian Journal of Biology
Cell adhesion molecules act as signal transducers from the extracellular environment to the cytoskeleton and the nucleus and consequently induce changes in the expression pattern of structural proteins.
MF. Izaguirre, MN. García-Sancho, LA. Miranda, J. Tomas, VH. Casco   +4 more
doaj   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Possible origins of macroscopic left-right asymmetry in organisms

, 2012
I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules.
A. Tamada, A. Varma, A. Vilfan, A.M. Heacock, A.R. Palmer, C. Ambrose, C. Arrieumerlou, C. McManus, C. Pohl, C.H. Wiggins, C.L. Henley, C.R. Cowan, C.S. Peskin, C.W. Wolgemuth, Christopher L. Henley, D. Vavylonis, D.S. Adams, D.W. Ehrhardt, E. Ben-Jacob, E. Ben-Jacob, E. Kawamura, E.C. Eren, E.C. Eren, E.E. Deinum, F. Ziebert, F.C. Frank, G. Salbreux, G.M. Grason, G.O. Wasteneys, H. Hamada, H.F. Romijn, I. Mabuchi, J. Chan, J. Chan, J. Cooke, J. Gore, J. Hagmann, J. Salje, J. Xu, J.A. Åström, J.F. Allard, J.F. Allard, J.F. Beausang, J.H.E. Cartwright, K. Taniguchi, L.F. Jones, L.Q. Wan, M. Levin, M. Levin, M. Levin, M. Mayer, M.E. Halpern, M.L. Manning, M.P. Wold, M.V. Danilchik, M.V. Thompson, M.Y. Ali, N. Hirokawa, N. Morone, N.A. Brown, N.H. Mendelson, N.H. Mendelson, P. Spéder, P. Spéder, R. Dixit, R. Kawamura, R. Kuroda, R.D. Kamien, R.D. Preston, R.J. Hawkins, R.J. Poole, R.M. Figge, S. Aw, S. Hozumi, S. Nonaka, S. Nonaka, S. Thitamadee, S. Wang, S.H. Tindemans, S.L. Shaw, S.S. Andrews, T. Hashimoto, T. Ishida, T. Kamasaki, T. Lionnet, T. Nishizaka, T. Okumura, T. Sun, T.-H. Chuan, V.A. Avertisov, V.A. Baulin, W. Lauga, W.B. Wood, W.B. Wood, W.B. Wood, W.R. DiLuzio, X.-Q. Shi, Y. Nakadera, Y. Shibazaki, Y. Wu, Y.B. Malashichev   +100 more
core   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

A Network of Cadherin-Mediated Interactions Polarizes Growth Cones to Determine Targeting Specificity [PDF]

, 2013
Tina Schwabe, Helen Neuert, Thomas R. Clandinin   +2 more
openalex   +1 more source