Results 231 to 240 of about 65,722 (350)
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source
Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion. [PDF]
Teng CS +4 more
europepmc +1 more source
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang +12 more
wiley +1 more source
Classical cadherins evolutionary constraints in primates is associated with their expression in the central nervous system. [PDF]
Petersen M +3 more
europepmc +1 more source
Funktionelle Analyse des Cadherin-Catenin-Komplexes in Pankreaskarzinomzelllinien
Björn Seidel
openalex +2 more sources
Traceless Regulation of Genetic Circuitry
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley +1 more source
Oncology Clinical Trials Targeting Members of the Cadherin Superfamily: A Review. [PDF]
Keeling J, Falchook G.
europepmc +1 more source
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu +12 more
wiley +1 more source

