Results 71 to 80 of about 1,197 (161)
Nanomedicines for the delivery of biologics [PDF]
, 2019 A special symposium of the Academy of Pharmaceutical Sciences Nanomedicines Focus Group reviewed the current status of the use of nanomedicines for the delivery of biologics drugs.
Desai, Arpan +10 more
core +6 more sources
Frontiers in Immunology, 2022 Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for ...
Christiane Desel +9 more
doaj +1 more source
Genital Chlamydia trachomatis: understanding the roles of innate and adaptive immunity in vaccine research. [PDF]
, 2014 Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease worldwide, and despite significant advances in chlamydial research, a prophylactic vaccine has yet to be developed.
Baud, D. +3 more
core +1 more source
Immunology &Cell Biology, Volume 103, Issue 9, Page 825-843, October 2025.Therapeutic cancer vaccines require CD8+ T‐cell activation for efficacy. This response can be enhanced by rationally designing polymeric nanoparticle adjuvants. The importance of antigen location for the adjuvanticity of polymeric nanoparticles has not been fully resolved.
Jorge Huete‐Carrasco +6 more
wiley +1 more source
Vaccine, 2015 CD4(+) T-cell priming is an essential step in vaccination due to the key role of T helper cells in driving both effector and memory immune responses. Here we have characterized in C57BL/6 mice the T helper subtype differentiation among tetramer-specific CD4(+) T cells primed by subcutaneous immunization with the tuberculosis vaccine antigen H56 plus ...
Prota, Gennaro +4 more
openaire +4 more sources
European Journal of Immunology, Volume 54, Issue 6, June 2024.Intranasal administration of spike protein antigen alone following an intramuscular prime with spike protein antigen adjuvanted with sulfated lactosylarchaeol (SLA) archaeosomes boosts systemic and mucosal immune responses, leading to protection from SARS‐CoV‐2 infection.
Gerard Agbayani +13 more
wiley +1 more source
, 2023 Malaria is a life-threatening protozoan parasite disease transmitted by mosquitoes, which infected approximately 228 million people worldwide in 2018, of which 405,000 people died. Even with existing control methods, such as mosquito nets and insecticides, as well as various therapies, resistances to these methods are increasing as well.
openaire +3 more sources
Principales sistemas de entrega de antígenos en Medicina Veterinaria y Humana [PDF]
, 2014 Las vacunas modernas se basan generalmente en proteínas recombinantes altamente purificadas. Esta alta pureza representa uno de los mayores avances en términos de seguridad, en comparación a las estrategias de vacunación tradicionales basadas en ...
Siel, Daniela +2 more
core +2 more sources
Local Th17/IgA immunity correlate with protection against intranasal infection with Streptococcus pyogenes. [PDF]
PLoS ONE, 2017 Streptococcus pyogenes (group A streptococcus, GAS) is responsible for a wide array of infections. Respiratory transmission via droplets is the most common mode of transmission but it may also infect the host via other routes such as lesions in the skin.
Rasmus Mortensen +5 more
doaj +1 more source
Scientific Reports, 2017 In the absence of a validated correlate of protection or robust animal models for human tuberculosis, Mycobacterial growth inhibition assays (MGIAs) aim to assess vaccines ability to inhibit mycobacterial growth in-vitro.
Christina Jensen +4 more
doaj +1 more source