CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury
Journal of Inflammation Research, 2016 Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
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The polymer and materials science of the bacterial fimbriae Caf1 [PDF]
Biomaterials Science, 2023 Fimbriae are long filamentous polymeric protein structures located upon the surface of bacteria. Often implicated in pathogenicity, the biosynthesis and function of fimbriae has been a productive topic of study for many decades.
David A. Fulton +2 more
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Subunits of the Histone Chaperone CAF1 Also Mediate Assembly of Protamine-Based Chromatin [PDF]
Cell Reports, 2013 One of the most dramatic forms of chromatin reorganization occurs during spermatogenesis, when the paternal genome is repackaged from a nucleosomal to a protamine-based structure. We assessed the role of the canonical histone chaperone CAF1 in Drosophila
Cécile M. Doyen +7 more
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Yersinia pestis Caf1 Protein: Effect of Sequence Polymorphism on Intrinsic Disorder Propensity, Serological Cross-Reactivity and Cross-Protectivity of Isoforms. [PDF]
PLoS ONE, 2016 Yersinia pestis Caf1 is a multifunctional protein responsible for antiphagocytic activity and is a key protective antigen. It is generally conserved between globally distributed Y. pestis strains, but Y. pestis subsp.
Pavel Kh Kopylov +9 more
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The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs [PDF]
Open Biology, 2016 Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of
Michał Pasternak +3 more
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BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation [PDF]
Nature Communications, 2016 BTG2 promotes mRNA poly(A) tail shortening and regulates cellular differentiation. Here, Stupfler et al. show that the BTG2 APRO domain interacts with PABPC1 RRM1, allowing the former to recruit and stimulate the poly(A) tail shortening activity of CAF1 ...
Benjamin Stupfler +3 more
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Interactions of CAF1-NOT complex components from Trypanosoma brucei [PDF]
F1000Research, 2017 The CAF1-NOT complex of Trypanosoma brucei , like that of other eukaryotes, contains several NOT proteins (NOT1, NOT3, NOT3/5, NOT10, and NOT11), NOT9/CAF40, and the CAF1 deadenylase, which targets 3' poly(A) tails.
Chaitali Chakraborty +6 more
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DREF Genetically Counteracts Mi-2 and Caf1 to Regulate Adult Stem Cell Maintenance.
PLoS Genetics, 2019 Active adult stem cells maintain a bipotential state with progeny able to either self-renew or initiate differentiation depending on extrinsic signals from the surrounding microenvironment.
Benjamin Angulo +5 more
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Caf1A usher possesses a Caf1 subunit-like domain that is crucial for Caf1 fibre secretion [PDF]
Biochemical Journal, 2008 The chaperone/usher pathway controls assembly of fibres of adhesive organelles of Gram-negative bacteria. The final steps of fibre assembly and fibre translocation to the cell surface are co-ordinated by the outer membrane proteins, ushers.
Sheila MacIntyre +22 more
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Thermal stability and rheological properties of the ‘non-stick’ Caf1 biomaterial
Biomedical Materials, 2017 WOS:000410928400001PubMed:28632140The ability to culture cells in three-dimensions has many applications, from drug discovery to wound healing. 3D cell culture methods often require appropriate scaffolds that mimic the cellular environments of different ...
Y. Ulusu +6 more
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