PTCDA adsorption on CaF2 thin films
Beilstein Journal of Nanotechnology, 2020 Thin insulating films are commonly employed for the electronic decoupling of molecules as they enable a preservation of the intrinsic molecular electronic functionality.
Philipp Rahe
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The chromatin assembly factor complex 1 (CAF1) and 5-Azacytidine (5-AzaC) affect cell motility in Src-transformed human epithelial cells [PDF]
, 2016 Tumor invasion into surrounding stromal tissue is a hallmark of high grade, metastatic cancers. Oncogenic transformation of human epithelial cells in culture can be triggered by activation of v-Src kinase, resulting in increased cell motility ...
Bamford +39 more
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Engineered mosaic protein polymers; a simple route to multifunctional biomaterials
Journal of Biological Engineering, 2019 Background Engineered living materials (ELMs) are an exciting new frontier, where living organisms create highly functional materials. In particular, protein ELMs have the advantage that their properties can be manipulated via simple molecular biology ...
Daniel T. Peters +3 more
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СAPSULAR ANTIGEN OF YERSINIA PESTIS
Инфекция и иммунитет, 2015 Plague is a zoonosis caused by gram-negative bacteria Yersinia pestis, which, as a rule, is transmitted to humans from septicemic rodents by the bites of infected fleas. This microbe killed more people than all of the wars in the human history. Y. pestis
L. A. Kadnikova +3 more
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Epigenetics & Chromatin, 2023 Background Classical studies on position effect variegation in Drosophila have demonstrated the existence of bi-modal Active/Silent state of the genes juxtaposed to heterochromatin.
Safia Mahabub Sauty, Krassimir Yankulov
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Role of Ccr4-Not complex in heterochromatin formation at meiotic genes and subtelomeres in fission yeast. [PDF]
, 2015 BACKGROUND: Heterochromatin is essential for chromosome segregation, gene silencing and genome integrity. The fission yeast Schizosaccharomyces pombe contains heterochromatin at centromeres, subtelomeres, and mating type genes, as well as at small ...
Bähler, Jürg +7 more
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MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment [PDF]
Journal of Biological Chemistry, 2010 Tristetraprolin (TTP) directs its target AU-rich element (ARE)-containing mRNAs for degradation by promoting removal of the poly(A) tail. The p38 MAPK pathway regulates mRNA stability via the downstream kinase MAPK-activated protein kinase 2 (MAPKAP kinase 2 or MK2), which phosphorylates and prevents the mRNA-destabilizing function of TTP. We show that
Marchese, F +5 more
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Caf1 of Yersinia pestis Forms Complex Highly Stable Protein Polymers and Hydrogel Scaffolds [PDF]
Biophysical Journal, 2016 Caf1 is a polymeric protein from the plague bacterium Y. pestis which is secreted via the chaperone-usher pathway and protects the pathogen from macrophages of the host's immune system by forming a protective layer around the cell. The 15.5kDa monomer has beta structure and resembles the extracellular matrix protein fibronectin.
Waller, Helen +2 more
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The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module [PDF]
, 2015 In eukaryotic cells, the shortening and removal of the poly(A) tail (deadenylation) of cytoplasmic mRNA is a key event in regulated mRNA degradation. A major enzyme involved in deadenylation is the Ccr4-Not deadenylase complex, which can be recruited to ...
Aslam +47 more
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RrmA regulates the stability of specific transcripts in response to both nitrogen source and oxidative stress [PDF]
, 2013 Differential regulation of transcript stability is an effective means by which an organism can modulate gene expression. A well-characterized example is glutamine signalled degradation of specific transcripts in Aspergillus nidulans. In the case of areA,
Caddick, M.X. +6 more
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