Yersinia pestis caf1Variants and the Limits of Plague Vaccine Protection [PDF]
Infection and Immunity, 2008 ABSTRACTYersinia pestis, the highly virulent agent of plague, is a biological weapon. Strategies that prevent plague have been sought for centuries, and immunization with live, attenuated (nonpigmented) strains or subunit vaccines with F1 (Caf1) antigen is considered effective.
Lauriane E, Quenee +4 more
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Molecular Plant-Microbe Interactions, 2014 To decipher the mechanism of pathogenicity in Sclerotinia sclerotiorum, a pathogenicity-defective mutant, Sunf-MT6, was isolated from a T-DNA insertional library.
Xueqiong Xiao +6 more
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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila [PDF]
The EMBO Journal, 2004 The CCR4-NOT complex is the major enzyme catalyzing mRNA deadenylation in Saccharomyces cerevisiae. We have identified homologs for almost all subunits of this complex in the Drosophila genome. Biochemical fractionation showed that the two likely catalytic subunits, CCR4 and CAF1, were associated with each other and with a poly(A)-specific 3 ...
Claudia, Temme +4 more
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Unraveling the molecular determinants of the anti-phagocytic protein cloak of plague bacteria.
PLoS Pathogens, 2022 The pathogenic bacterium Yersina pestis is protected from macrophage engulfment by a capsule like antigen, F1, formed of long polymers of the monomer protein, Caf1.
Daniel T Peters +7 more
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The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases [PDF]
Nature Structural & Molecular Biology, 2019 The 3' poly(A) tail of messenger RNA is fundamental to regulating eukaryotic gene expression. Shortening of the poly(A) tail, termed deadenylation, reduces transcript stability and inhibits translation. Nonetheless, the mechanism for poly(A) recognition by the conserved deadenylase complexes Pan2-Pan3 and Ccr4-Not is poorly understood.
Terence T. L. Tang +3 more
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Indices of immunity (II) induced by the three Caf1 isoforms. [PDF]
, 2016 Indices of immunity (II) induced by the three Caf1 isoforms.
Mikhail E. Platonov (262787) +9 more
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PTCDA adsorption on CaF2 thin films
Beilstein Journal of Nanotechnology, 2020 Thin insulating films are commonly employed for the electronic decoupling of molecules as they enable a preservation of the intrinsic molecular electronic functionality.
Philipp Rahe
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Caf1 regulates translocation of ribonucleotide reductase by releasing nucleoplasmic Spd1-Suc22 assembly [PDF]
Nucleic Acids Research, 2007 Appropriate supply of deoxyribonucleotides by the ribonucleotide reductase (RNR) complex is essential for DNA replication and repair. One recent model for the RNR activation in Schizosaccharomyces pombe is translocation of the regulatory subunit Suc22 from the nucleoplasm to the cytoplasm.
Takahashi, Shinya +3 more
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Protein engineering of Caf1 from the plague bacterium Yersinia pestis for tissue engineering applications [PDF]
, 2016 30th Anniversary Symposium of the Protein-Society -- JUL 16-19, 2016 -- Baltimore, MDWOS:000387152400105Institute of Cellular and Molecular Bioscience, Medical School, University of Newcastle, UK, 2 Department of Bioengineering, Faculty of Engineering ...
Peters, Daniel +3 more
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Engineered mosaic protein polymers; a simple route to multifunctional biomaterials
Journal of Biological Engineering, 2019 Background Engineered living materials (ELMs) are an exciting new frontier, where living organisms create highly functional materials. In particular, protein ELMs have the advantage that their properties can be manipulated via simple molecular biology ...
Daniel T. Peters +3 more
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