Results 51 to 60 of about 3,723 (183)
Structural and Functional Similarity Between Yersinia Pestis Capsular Protein Caf1 and Human Interleukin-1β [PDF]
, 2001 A comparative study of the structural and functional properties of recombinant Yersinia pestis Caf1 and human IL-1β was performed. According to Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) data, IL-1β and Caf1 are typical β ...
Fink, Anthony L. +12 more
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СAPSULAR ANTIGEN OF YERSINIA PESTIS
Инфекция и иммунитет, 2015 Plague is a zoonosis caused by gram-negative bacteria Yersinia pestis, which, as a rule, is transmitted to humans from septicemic rodents by the bites of infected fleas. This microbe killed more people than all of the wars in the human history. Y. pestis
L. A. Kadnikova +3 more
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Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation [PDF]
Molecular Cell, 2009 MicroRNAs (miRNAs) inhibit mRNA expression in general by base pairing to the 3'UTR of target mRNAs and consequently inhibiting translation and/or initiating poly(A) tail deadenylation and mRNA destabilization. Here we examine the mechanism and kinetics of miRNA-mediated deadenylation in mouse Krebs-2 ascites extract.
Fabian, Marc R +16 more
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Epigenetics & Chromatin, 2023 Background Classical studies on position effect variegation in Drosophila have demonstrated the existence of bi-modal Active/Silent state of the genes juxtaposed to heterochromatin.
Safia Mahabub Sauty, Krassimir Yankulov
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Effect of Caf1 mutant proteins on the phagocytosis of polystyrene beads. [PDF]
, 2022 Polystyrene beads were coated with purified Caf1 polymers and incubated with J774.A1 macrophages for 2 h before fixation. Non-phagocytosed beads were visualised by incubation with a mouse anti-Caf1 antibody, followed by a goat anti-mouse Alexa Fluor 555 ...
Daniel T. Peters (4345414) +7 more
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X-linked RBBP7 mutation causes maturation arrest and testicular tumors
The Journal of Clinical Investigation, 2023 Maturation arrest (MA) is a subtype of non-obstructive azoospermia, and male infertility is a known risk factor for testicular tumors. However, the genetic basis for many affected individuals remains unknown.
Jingping Li +7 more
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CCR4 and CAF1 deadenylases have an intrinsic activity to remove the post-poly(A) sequence [PDF]
RNA, 2016 MicroRNAs (miRNAs) recruit the CCR4–NOT complex, which contains two deadenylases, CCR4 and CAF1, to promote shortening of the poly(A) tail. Although both CCR4 and CAF1 generally have a strong preference for poly(A) RNA substrates, it has been reported from yeast to humans that they can also remove non-A residues in vitro to various degrees. However, it
Niinuma, Sho +2 more
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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex
Frontiers in Genetics, 2013 The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation.
Gerlof Sebastiaan Winkler +1 more
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The biological function of the WD40 repeat‐containing protein p55/Caf1 in Drosophila [PDF]
Developmental Dynamics, 2012 AbstractBackground: The p55 family WD40 repeat‐containing histone chaperone proteins are components of several chromatin regulatory complexes (such as PRC2, NURF and CAF‐1) and interact with histone H4, yet their functional relevance in vivo is unclear.
Pei, Wen, Zhenghui, Quan, Rongwen, Xi
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G3: Genes, Genomes, Genetics, 2018 In “Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element,” Leung et al. (2017) improved contigs attributed to the Muller F element from the original CAF1 assembly, and used them to conclude that most ...
Julie C. Dunning Hotopp, Lisa Klasson
doaj +1 more source