Results 51 to 60 of about 6,761 (193)
Conservation of the deadenylase activity of proteins of the Caf1 family in human [PDF]
RNA, 2005 The yeast Pop2 protein, belonging to the eukaryotic Caf1 family, is required for mRNA deadenylation in vivo. It also catalyzes poly(A) degradation in vitro, even though this property has been questioned. Caf1 proteins are related to RNase D, a feature supported by the recently published structure of Pop2.
Claire, Bianchin +4 more
openaire +2 more sources
Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex
Frontiers in Genetics, 2013 The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation.
Gerlof Sebastiaan Winkler +1 more
doaj +1 more source
The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs [PDF]
Open Biology, 2016 Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of
Michał Pasternak +3 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2018 In “Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element,” Leung et al. (2017) improved contigs attributed to the Muller F element from the original CAF1 assembly, and used them to conclude that most ...
Julie C. Dunning Hotopp, Lisa Klasson
doaj +1 more source
Phase-field simulation of core-annular pipe flow
, 2019 Phase-field methods have long been used to model the flow of immiscible fluids. Their ability to naturally capture interface topological changes is widely recognized, but their accuracy in simulating flows of real fluids in practical geometries is not ...
Avila, Marc +3 more
core +1 more source
Chromatin structure and DNA damage repair [PDF]
, 2008 The integrity of the genome is continuously challenged by both endogenous and exogenous DNA damaging agents. These damaging agents can induce a wide variety of lesions in the DNA, such as double strand breaks, single strand breaks, oxidative lesions and ...
Dinant Christoffel +2 more
core +2 more sources
The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control. [PDF]
PLoS ONE, 2014 Eukaryotic cells control their proteome by regulating protein production and protein clearance. Protein production is determined to a large extent by mRNA levels, whereas protein degradation depends mostly upon the proteasome.
David Halter +2 more
doaj +1 more source
Lower bounds on entanglement measures from incomplete information
, 2008 How can we quantify the entanglement in a quantum state, if only the expectation value of a single observable is given? This question is of great interest for the analysis of entanglement in experiments, since in many multiparticle experiments the state ...
G. K. Brennen +7 more
core +1 more source
Conformal Phase Diagram of Complete Asymptotically Free Theories [PDF]
, 2016 We investigate the ultraviolet and infrared fixed point structure of gauge-Yukawa theories featuring a single gauge coupling, Yukawa coupling and scalar self coupling.
Pica, Claudio +2 more
core +2 more sources
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation
Epigenetics & Chromatin, 2023 Background Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into chromatin. H3.
Syed Nabeel-Shah +12 more
doaj +1 more source