Results 71 to 80 of about 4,758 (202)
G3: Genes, Genomes, Genetics, 2018 In “Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element,” Leung et al. (2017) improved contigs attributed to the Muller F element from the original CAF1 assembly, and used them to conclude that most ...
Julie C. Dunning Hotopp, Lisa Klasson
doaj +1 more source
The structure of Yersinia pestis Caf1 polymer in free and adjuvant bound states
Caf1 of the plague bacterium, Yersinia pestis is a polymeric virulence factor and vaccine component. formed from monomers by a donor strand exchange (DSE) mechanism. Here. EM images of Caf1 reveal flexible polymers up to 1 5 mu m long (4 MDa).
Watkinson A +3 more
core +5 more sources
PLoS ONE, 2020 BACKGROUND:Several tests are available for plague confirmation but bacteriological culture with Yersinia pestis strain isolation remains the gold standard according to the World Health Organization.
Lovasoa N Randriantseheno +4 more
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The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control. [PDF]
PLoS ONE, 2014 Eukaryotic cells control their proteome by regulating protein production and protein clearance. Protein production is determined to a large extent by mRNA levels, whereas protein degradation depends mostly upon the proteasome.
David Halter +2 more
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Cancer Science, EarlyView.Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara +8 more
wiley +1 more source
British Journal of DermatologyBACKGROUND Laminin-332 is a key extracellular matrix (ECM) protein that supports keratinocyte adhesion, migration, and re-epithelialisation during wound healing.
Yu Nie +8 more
semanticscholar +1 more source
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation
Epigenetics & Chromatin, 2023 Background Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into chromatin. H3.
Syed Nabeel-Shah +12 more
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Advanced Science, Volume 13, Issue 43, 3 August 2026.ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun +19 more
wiley +1 more source
CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells. [PDF]
PLoS Genetics, 2006 During mammalian development, chromatin dynamics and epigenetic marking are important for genome reprogramming. Recent data suggest an important role for the chromatin assembly machinery in this process. To analyze the role of chromatin assembly factor 1
Martin Houlard +6 more
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Advanced Science, Volume 13, Issue 47, 24 August 2026.This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan +6 more
wiley +1 more source