Results 71 to 80 of about 3,723 (183)
CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells. [PDF]
PLoS Genetics, 2006 During mammalian development, chromatin dynamics and epigenetic marking are important for genome reprogramming. Recent data suggest an important role for the chromatin assembly machinery in this process. To analyze the role of chromatin assembly factor 1
Martin Houlard +6 more
doaj +1 more source
Journal of Cardiovascular Development and Disease, 2023 Methyltransferases regulate transcriptome dynamics during development and aging, as well as in disease. Various methyltransferases have been linked to heart disease, through disrupted expression and activity, and genetic variants associated with ...
Jun-yi Zhu +5 more
doaj +1 more source
Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 1973-2000, July 2026.Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu +7 more
wiley +1 more source
Research in Molecular Medicine, 2018 Background: Yersinia pestis and Francisella tularensis cause plague and tularemia, which are known as diseases of the newborn and elderly, respectively.
Nafiseh Pourmahdi +3 more
doaj +1 more source
Biochemical and biophysical characterization of the deadenylase CrCaf1 from Chlamydomonas reinhardtii. [PDF]
PLoS ONE, 2013 The modulation of mRNA turnover has been increasingly recognized as a hotpoint for gene expression regulation at the post-transcriptional level. In eukaryotic cells, most mRNAs are degraded via the deadenylation-dependent pathway, in which the removal of
Jia-Quan Zhang +2 more
doaj +1 more source
Regulation of eukaryotic mRNA deadenylation and degradation by the Ccr4-Not complex
Frontiers in Cell and Developmental Biology, 2023 Accurate and precise regulation of gene expression programmes in eukaryotes involves the coordinated control of transcription, mRNA stability and translation.
Lorenzo Pavanello +2 more
doaj +1 more source
MedComm, Volume 7, Issue 6, June 2026.ABSTRACT Betel nut chewing is a major etiological factor for oral squamous cell carcinoma (OSCC), yet its mechanistic underpinnings remain poorly defined. Here, we performed single‐cell RNA sequencing and spatial transcriptomics from six OSCC patients to comprehensively dissect the tumor microenvironment (TME) dynamics and cellular heterogeneity ...
Wei Dong +6 more
wiley +1 more source
Caf1 of Yersinia pestis Forms Complex Highly Stable Protein Polymers and Hydrogel Scaffolds [PDF]
Biophysical Journal, 2016 Caf1 is a polymeric protein from the plague bacterium Y. pestis which is secreted via the chaperone-usher pathway and protects the pathogen from macrophages of the host's immune system by forming a protective layer around the cell. The 15.5kDa monomer has beta structure and resembles the extracellular matrix protein fibronectin.
Waller, Helen +2 more
openaire +1 more source
Biology Open, 2019 Cell-fate maintenance is important to preserve the variety of cell types that are essential for the formation and function of tissues. We previously showed that the acetylated histone-binding protein BET-1 maintains cell fate by recruiting the histone ...
Yukimasa Shibata +2 more
doaj +1 more source
Ambient stable quantitative PCR reagents for the detection of Yersinia pestis. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Although assays for detecting Yersinia pestis using TaqMan probe-based real-time PCR have been developed for years, little is reported on room-temperature-stable PCR reagents, which will be invaluable for field epidemic surveillance ...
Shi Qu +6 more
doaj +1 more source