Results 81 to 90 of about 4,758 (202)

Simple and Rapid Detection of Yersinia pestis and Francisella tularensis Using Multiplex-PCR: Molecular Detection of Yersinia pestis and Francisella tularensis

open access: yesResearch in Molecular Medicine, 2018
Background: Yersinia pestis and Francisella tularensis cause plague and tularemia, which are known as diseases of the newborn and elderly, respectively.
Nafiseh Pourmahdi   +3 more
doaj   +1 more source

Biochemical and biophysical characterization of the deadenylase CrCaf1 from Chlamydomonas reinhardtii. [PDF]

open access: yesPLoS ONE, 2013
The modulation of mRNA turnover has been increasingly recognized as a hotpoint for gene expression regulation at the post-transcriptional level. In eukaryotic cells, most mRNAs are degraded via the deadenylation-dependent pathway, in which the removal of
Jia-Quan Zhang   +2 more
doaj   +1 more source

Engineered Caf1 Protein Polymers form Tuneable Bioactive Hydrogel Scaffolds [PDF]

open access: yesBiophysical Journal, 2018
H. Waller   +4 more
semanticscholar   +2 more sources

Revisiting Pluripotency Acquisition: A Unified Framework for Reprogramming Strategies

open access: yesDevelopment, Growth &Differentiation, Volume 68, Issue 6, August 2026.
ABSTRACT The traditional hierarchical view of totipotent cells generating diverse lineages of terminally differentiated cells was challenged by the discovery of induced pluripotent stem cells (iPSCs). This breakthrough demonstrated that the ectopic expression of four transcription factors, Oct4, Sox2, Klf4, and c‐Myc (OSKM), can reprogram somatic cells
Anamika Datta, Kunimasa Ohta
wiley   +1 more source

Ambient stable quantitative PCR reagents for the detection of Yersinia pestis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: Although assays for detecting Yersinia pestis using TaqMan probe-based real-time PCR have been developed for years, little is reported on room-temperature-stable PCR reagents, which will be invaluable for field epidemic surveillance ...
Shi Qu   +6 more
doaj   +1 more source

Regulation of eukaryotic mRNA deadenylation and degradation by the Ccr4-Not complex

open access: yesFrontiers in Cell and Developmental Biology, 2023
Accurate and precise regulation of gene expression programmes in eukaryotes involves the coordinated control of transcription, mRNA stability and translation.
Lorenzo Pavanello   +2 more
doaj   +1 more source

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications

open access: yesWIREs RNA, Volume 17, Issue 4, July/August 2026.
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus   +5 more
wiley   +1 more source

Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in Caenorhabditis elegans

open access: yesBiology Open, 2019
Cell-fate maintenance is important to preserve the variety of cell types that are essential for the formation and function of tissues. We previously showed that the acetylated histone-binding protein BET-1 maintains cell fate by recruiting the histone ...
Yukimasa Shibata   +2 more
doaj   +1 more source

Pentatricopeptide repeat proteins in crops: Advances in functional mechanisms and breeding applications

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 7, Page 1973-2000, July 2026.
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu   +7 more
wiley   +1 more source

Indices of immunity (II) induced by the three Caf1 isoforms.

open access: yes, 2016
Indices of immunity (II) induced by the three Caf1 isoforms.
Mikhail E. Platonov (262787)   +9 more
core   +1 more source

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