Dental Journal, 2021 Background: In Indonesia, the prevalence of dental and oral problems is still high at 57.6% in 2018, especially periodontitis at 74.1%. Peptidoglycan is an essential component of the bacterial cell wall.
Imelia Arifatus Sani +4 more
doaj +1 more source
A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model. [PDF]
Antioxidants (Basel), 2022 Shahin NN, Shamma RN, Ahmed IS.
europepmc +3 more sources
Caffeic Acid Phenethyl Ester and Therapeutic Potentials [PDF]
BioMed Research International, 2014 Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different ...
Ghulam Murtaza +6 more
openaire +3 more sources
Propolis and its constituents against cardiovascular risk factors including obesity, hypertension, atherosclerosis, diabetes, and dyslipidemia: A comprehensive review [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Cardiovascular diseases (CVDs) are some of the major causes of death worldwide. The modern lifestyle elevates the risk of CVDs. CVDs have several risk factors such as obesity, dyslipidemia, atherosclerosis, hypertension, and diabetes.
Arian Khoshandam +4 more
doaj +1 more source
Proceedings, 2020 : We identified and quantified by LC-MS/MS 11 (quercetin, galangin, pinocembrin, kaempferol, vanillin, chrysin, gallic acid, p-coumaric acid, trans-ferulic acid, caffeic acid, and caffeic acid phenethyl ester) out of the 21 polyphenolic compounds we ...
Madalina Maria Nichitoi +5 more
doaj +1 more source
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties [PDF]
FEBS Letters, 1993 Caffeic acid phenethyl ester, an active component of propolis extract, inhibits 5‐lipoxygenase in the micromolar concentration range. The inhibition is of an uncompetitive type, i.e. the inhibitor binds to the enzyme‐substrate complex but not to the free enzyme. Caffeic acid phenethyl ester also exhibits antioxidant properties. At a concentration of 10
Natalia V. Sumbatyan +5 more
openaire +3 more sources
Effect of Propolis on moderate persistent asthma: A phase two randomized, double blind, controlled clinical trial [PDF]
Avicenna Journal of Phytomedicine, 2021 Objective: The aims of this study was to determine the effect of Propolis (resinous mixture that honey bees produce by mixing saliva and beeswax) on clinical and physiological findings of moderate persistent asthma.
Majid Mirsadraee +4 more
doaj +1 more source
THE INHIBITORY EFFECT OF PROPOLIS AND CAFFEIC ACID PHENETHYLESTER ON CYCLOOXYGENASE ACTIVITY IN J774 MACROPHAGES. [PDF]
, 2002 The effect of an ethanolic extract of propolis, with and without CAPE, and some of its components on cyclooxygenase (COX-1 and COX-2) activity in J774 macrophages has been investigated.
BORRELLI, FRANCESCA +5 more
core +1 more source
Activity of Caffeic Acid Phenethyl Ester in Caenorhabditis Elegans [PDF]
Future Medicinal Chemistry, 2016 Caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE), the major constituent of propolis, is able to increase the survival of the nematode Caenorhabditis elegans after infection with the fungal pathogen Candida albicans.CAPE increases the expression of several antimicrobial proteins involved in the immune response to C. albicans.
Julia Munro +11 more
openaire +2 more sources
Caffeic Acid Derivatives Inhibit the Growth of Colon Cancer: Involvement of the PI3-K/Akt and AMPK Signaling Pathways [PDF]
, 2014 The aberrant regulation of phosphatidylinositide 3-kinases (PI3-K)/Akt, AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (m-TOR) signaling pathways in cancer has prompted significant interest in the suppression of these pathways to ...
Chiang, En-Pei Isabel +6 more
core +2 more sources