Results 51 to 60 of about 3,383 (174)

Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment

Stem Cell Research & Therapy, 2017
Background Several studies have suggested that caffeic acid phenethyl ester (CAPE) can induce the expression of hypoxia inducible factor-1α (HIF-1α) protein.
Xiaofang Chen, Yi Han, Bowen Zhang, Yiming Liu, Sihan Wang, Tuling Liao, Ziliang Deng, Zeng Fan, Jing Zhang, Lijuan He, Wen Yue, Yanhua Li, Xuetao Pei   +12 more
doaj   +1 more source

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

Water-Mediated Synthesis of (E)-3-(1-Methyl-1H-benzo[d]imidazol-5-yl)-N-phenethylacrylamide, a Caffeic Acid Phenethyl Amide Analogue

Molbank
Caffeic acid phenethyl ester (CAPE) is a phenolic natural product with diverse biological activities, notably anticancer properties. However, its ester group is metabolically unstable.
Muppidi Subbarao, Sean M. Kerwin
doaj   +1 more source

Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes

PPAR Research, 2016
Hypertrophic obesity inhibits activation of peroxisome proliferators-activated receptor gamma (PPARγ), considered the key mediator of the fully differentiated and insulin sensitive adipocyte phenotype.
Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo   +9 more
doaj   +1 more source

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Antiviral Properties of Caffeic Acid Phenethyl Ester and Its Potential Application

Journal of Intercultural Ethnopharmacology, 2015
Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies.
Erdemli, Hacı Kemal, Akyol, Sumeyya, Armutcu, Ferah, Akyol, Omer   +3 more
openaire   +4 more sources

Probiotic Supplementation With Bifidobacterium longum Subsp. Longum BL21 Improves Glycemic Control and Modulates Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Supplementation with BL21 led to a significant reduction in HbA1c levels (p = 0.026) compared with placebo. Non‐significant trends toward reduction were also observed for FBG and insulin resistance. The intervention was well tolerated, with a safety profile comparable to placebo.
Chengsheng Zhu, Yinhua Liu, Yanyan Chen, Zhiying Wang, Ya Gao, Fei Xu, Junyi Huang   +6 more
wiley   +1 more source

Beer Production With Umbu (Spondias tuberosa) Using Conventional and Nonconventional Yeast

Journal of Food Science, Volume 91, Issue 1, January 2026.
ABSTRACT This study evaluated the fermentation performance and bioactive properties of beers produced by Pichia kluyveri L131 and commercial Saccharomyces pastorianus, individually and in coculture, in wort enriched with umbu pulp. Fermentation profiles were assessed over 12 days, focusing on yeast population dynamics, carbohydrate consumption, and ...
Diego Pádua de Almeida, Hygor Lendell Silva de Souza, Ana Luiza Dozol, Mariana Moysés Delorme, Vanessa Naciuk Castelo‐Branco, Adriene Ribeiro Lima, Alexandre Soares dos Santos, Nadia Nara Batista, Rosane Freitas Schwan, Gustavo Molina, Cintia Lacerda Ramos   +10 more
wiley   +1 more source

From Hive to Health: Anti‐Influenza Properties of Bee Products

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Bee products have been long adapted as a natural remedy since centuries ago and studied for their bioactive properties including antimicrobial, anti‐inflammatory, antioxidant, and anticancer effects. Viral infections, including influenza, remain a significant global public health complication signifying the urgency for the development of alternative ...
Wei Wei Loo, Hien Tet Lai, Ji Wei Tan, Elena Sorrentino   +3 more
wiley   +1 more source

The Immunoregulatory Effects of Caffeic Acid Phenethyl Ester on the Cytokine Secretion of Peripheral Blood Mononuclear Cells From Asthmatic Children

Pediatrics and Neonatology, 2011
Asthma is a chronic inflammatory disease of the airways for which current treatments are mainly based on pharmacological interventions, such as glucocorticoid therapy.
Leticia Bautista Sy, Li-King Yang, Chiau-Juno Chiu, Wen-Mein Wu   +3 more
doaj   +1 more source