Results 131 to 140 of about 82,791 (297)

Data_Sheet_2_CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.PDF

open access: yes, 2019
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151)   +11 more
core   +1 more source

Illuminating Streptomyces: Raman Spectroscopy for Antibiotic Detection and Monitoring

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectroscopy provides a non‐destructive, label‐free approach for studying the chemical diversity of Streptomyces. This review presents its application from detection to chemical characterization of secondary metabolites and monitoring of biosynthetic processes.
Adéla Mikulová   +6 more
wiley   +1 more source

Calcineurin as a Nociceptor Modulator

open access: yesPain Physician, 2009
Calcineurin may be involved in affecting nociceptive processes in multiple circumstances. It is conceivable that interfering with calcineurin’s normal role in contributing to glial resting membrane potential, via its effects on the ion channel (TRESK) [tandem-pore-domain weakly inward rectifying potassium channels (TWIK)-related spinal cord potassium ...
openaire   +2 more sources

Data_Sheet_4_CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.PDF

open access: yes, 2019
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151)   +11 more
core   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori   +9 more
wiley   +1 more source

When Explant Surprises: Management and Outcomes of Hepatocellular Carcinoma Beyond Milan Criteria Discovered Post‐Transplant‐ A Narrative Review of Literature

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Liver transplantation (LT) is the definitive treatment for early hepatocellular carcinoma (HCC), based on established criteria. Pre‐transplant imaging occasionally underestimates the tumor burden or biological aggressiveness, leading to explant pathology that exceeds the projection criteria, such as Milan.
Serkan Sucu   +2 more
wiley   +1 more source

Nsp1 facilitates SARS-CoV-2 replication through calcineurin-NFAT signaling

open access: yesmBio
SARS-CoV-2, the causative agent of COVID-19, has been intensely studied in search of effective antiviral treatments. The immunosuppressant cyclosporine A (CsA) has been suggested to be a pan-coronavirus inhibitor, yet its underlying mechanism remained ...
Wai-Yin Lui   +7 more
doaj   +1 more source

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz   +2 more
wiley   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

open access: yesJEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau   +11 more
wiley   +1 more source

Redoxregulation der Protein-Serin/Threonin-Phosphatase Calcineurin

open access: yes, 2002
Reactive oxygen species (ROS) are now recognized as important mediators of the cellular responses to environmental changes. Reversible protein phosphorylation appears to be one of the major intracellular signal transduction mechanisms modulated by ROS ...
Namgaladze, Dmitry
core   +1 more source

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