Results 111 to 120 of about 78,892 (304)
Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment
JEADV Clinical Practice, EarlyView.ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley +1 more source
, 2019 Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151) +11 more
core +1 more source
Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center
JEADV Clinical Practice, EarlyView.ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres +4 more
wiley +1 more source
Calcineurin in human heart hypertrophy.
, 2002 peer reviewedBACKGROUND: In animal models, increased signaling through the calcineurin pathway has been shown to be sufficient for the development of cardiac hypertrophy. Calcineurin activity has been reported to be elevated in the myocardium of patients
Schuh, K. +23 more
core +1 more source
Calcium-directed therapy in acute pancreatitis
Медицина неотложных состоянийBackground. Acute pancreatitis (AP) is a common and potentially life-threatening disease with high rates of complications and mortality. One of its key pathogenic mechanisms is disruption of calcium homeostasis in pancreatic acinar cells.
С.М. Чуклін, С.С. Чуклін
doaj +1 more source
More Evidence Supports the Association of Ppp3cc with Schizophrenia
, 2008 Calcineurin is a calcium/calmodulin-dependent protein phosphatase composed of two subunits; a regulatory subunit of calcineurin B (CNB), and a catalytic subunit of calcineurin A (CNA).
劉玉麗;范盛娟;劉智民;張倩青;楊偉志;洪舜郁;俞松良;黃宗正;謝明憲;劉震鐘;莊明敏;鄔哲源;陳為堅;胡海國 +1 more
core
, 2019 Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151) +11 more
core +1 more source
陆军军医大学学报Objective Calcineurin (CaN) is implicated in regulating hippocampal astrocytic excitatory amino acid transporter 1 (EAAT1) and 2 (EAAT2) expression. This study investigates whether tacrolimus (FK506) reduces epileptogenesis by upregulating EAAT1 and ...
CHEN Changling, YE Lan
doaj +1 more source
, 2018 The protein phosphatase calcineurin is central to Ca2+ signaling pathways from yeast to humans. Full activation of calcineurin requires Ca2+ binding to the regulatory subunit CNB, comprised of four Ca2+-binding EF hand domains, and recruitment of Ca2 ...
Kerri Waters +6 more
core +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Seronegative myasthenia gravis (SNMG) is characterized by the absence of detectable autoantibodies against known MG targets, despite clinical and electrophysiological evidence of a postsynaptic neuromuscular junction disorder. The aim of this systematic review was to better define clinical features, diagnostic clues and treatment outcome of ...
Massimiliano Ugo Verza +6 more
wiley +1 more source