Results 101 to 110 of about 78,892 (304)

Generation of calcineurin inhibitor resistant EBV-CTLs for the treatment of post transplant lymphoma

open access: yes, 2010
Epstein Barr Virus driven post transplant lymphoproliferative disease (PTLD) is a serious complication following either stem cell or solid organ transplantation (SOT), occurring as a result of suppressed cellular immunity.
Brewin, J.J.
core  

Calcineurin in Animal Behavior

open access: yesMolecules and Cells, 2004
The conserved Ca2+/calmodulin-dependent phosphatase calcineurin has been shown to be involved in numerous and diverse functions both at the cellular and organism level. Recent genetic and pharmacological studies in animals including C. elegans, Drosophila, Aplysia, rat and mice have also implicated calcineurin in behavior, particularly in the ...
Jin Il, Lee, Joohong, Ahnn
openaire   +2 more sources

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz   +2 more
wiley   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

open access: yesJEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau   +11 more
wiley   +1 more source

Data_Sheet_5_CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.PDF

open access: yes, 2019
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151)   +11 more
core   +1 more source

CABIN1 펩타이드를 이용한 대체 calcineurin 억제제 개발 [PDF]

open access: yes, 2022
학위논문(박사) -- 서울대학교대학원 : 융합과학기술대학원 분자의학 및 바이오제약학과, 2022. 8. 윤홍덕.The C-terminal fragment of calcineurin binding protein-1 (CABIN1) interacts with calcineurin and represses the transcriptional activity of nuclear factor of activated T cells (NFAT).
이상호
core  

Calcineurin-Modulated Antimicrobial Peptide Expression Is Required for the Development of Helicoverpa armigera

open access: yesFrontiers in Physiology, 2019
Helicoverpa armigera is a universal pest around the world that has been extensively used as a model organism for agricultural pests. Calcineurin (CAN) is an important Ca2+-dependent phosphatase that is participated in various biological pathways.
Jizhen Wei   +7 more
doaj   +1 more source

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy   +5 more
wiley   +1 more source

Combination of nifedipine and subtherapeutic dose of cyclosporin additively suppresses mononuclear cells activation of patients with rheumatoid arthritis and normal individuals via Ca2+-calcineurin-nuclear factor of activated T cells pathway

open access: yes, 2014
Abnormal Ca2+-mediated signalling contributes to the pathogenesis of rheumatoid arthritis (RA). However, the potential implication of calcium channel blocker in RA remained unknown.
Lai, N-S.;Yu, C-L.;Yin, W-Y.;Yu, H-C.;Huang, H-B.;Tung, C-H.;Lu, M-C.   +1 more
core  

Data_Sheet_2_CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.PDF

open access: yes, 2019
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I.
Florence Carreras (1806151)   +11 more
core   +1 more source

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