Results 61 to 70 of about 662,429 (302)
Case Reports in Medicine, 2013 Thrombotic microangiopathy (TMA), a severe complication of renal transplantation, is a pathological process involving microvascular occlusion, thrombocytopenia, and microangiopathic hemolytic anemia.
Federico Cicora +3 more
doaj +1 more source
Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation [PDF]
, 2009 CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by ...
Crompton, M. +7 more
core +1 more source
Advanced Science, EarlyView.B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu +4 more
wiley +1 more source
Case Reports in Pediatrics, 2021 Granuloma gluteale infantum is a rare complication of irritant contact dermatitis. For the treatment of granuloma gluteale infantum, the diaper area should be kept clean and dry and the source of skin irritation should be removed or mitigated.
Alexander K. C. Leung +2 more
doaj +1 more source
Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments
Advanced Science, EarlyView.Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang +10 more
wiley +1 more source
New concepts to individualize calcineurin inhibitor therapy in renal allograft recipients
Saudi Journal of Kidney Diseases and Transplantation, 2010 A maximum of efficacy with a minimum of toxicity is the ultimate goal of immuno-suppressive therapy. Calcineurin inhibitors are widely used as immunosuppressive drugs, and there is still a discussion about the optimal blood levels of cyclosporine A (CsA)
Sommerer Claudia +3 more
doaj
Current Oncology, 2023 The purpose of this systematic review and meta-analysis was to compare the risk of non-melanoma skin cancer (NMSC) and melanoma development in renal transplant recipients who receive calcineurin inhibitors to that of patients treated with other ...
Aleksandra Kulbat +6 more
doaj +1 more source
Calcineurin inhibitorok hatása humán podocyták életképességére
, 2021 A podocyták rendkívül fontos szerepet töltenek be a filtrációs barrier fenntartásában és a fehérjék vizeletből való visszatartásában, mely feladatukat különleges morfológiájuk és sejtkapcsoló struktúráik segítségével látják el.
Racskó, Márk
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Advanced Science, EarlyView.This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou +4 more
wiley +1 more source
Generation of calcineurin inhibitor resistant EBV-CTLs for the treatment of post transplant lymphoma [PDF]
, 2010 Epstein Barr Virus driven post transplant lymphoproliferative disease (PTLD) is a serious complication following either stem cell or solid organ transplantation (SOT), occurring as a result of suppressed cellular immunity.
Brewin, J.J.
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