Results 11 to 20 of about 295,986 (313)
Calcium channel blockers- Induced iatrogenic gingival hyperplasia: Case series
Journal of Pharmacy and Bioallied Sciences, 2023 Hypertension rightfully termed as “Silent killer” is associated with increase in morbidity and mortality when left untreated. Calcium channel blockers are the most commonly prescribed first-line anti-hypertensive drugs in India.
G Agnes Golda Priyadarshini +4 more
doaj +1 more source
Calcium Channel Blockers [PDF]
The Journal of Clinical Hypertension, 2011 KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Calcium channel blockers, which dilate arteries by reducing calcium flux into cells, effectively lower blood pressure, especially in combination with other drugs, and some formulations of agents of this class are approved for treating angina or cardiac dysrhythmias.
William J. Elliott, C. Venkata S. Ram
openaire +3 more sources
Calcium Channel Antagonist Toxicity
MedEdPORTAL, 2014 Introduction This simulation case was designed to teach emergency medicine physicians, pediatricians, and other health care providers about the clinical presentation, stabilization, and medical management of the patient with suspected or proven toxic ...
Elaine Fielder +2 more
doaj +1 more source
Cholesterol influences voltage-gated calcium channels and BK-type potassium channels in auditory hair cells. [PDF]
PLoS ONE, 2011 The influence of membrane cholesterol content on a variety of ion channel conductances in numerous cell models has been shown, but studies exploring its role in auditory hair cell physiology are scarce.
Erin K Purcell +3 more
doaj +1 more source
eLife, 2014 TMEM16A forms calcium-activated chloride channels (CaCCs) that regulate physiological processes such as the secretions of airway epithelia and exocrine glands, the contraction of smooth muscles, and the excitability of neurons.
Jason Tien +6 more
doaj +1 more source
A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity. [PDF]
PLoS ONE, 2013 All subtypes of KCNQ channel subunits (KCNQ1-5) require calmodulin as a co-factor for functional channels. It has been demonstrated that calmodulin plays a critical role in KCNQ channel trafficking as well as calcium-mediated current modulation. However,
Anastasia Kosenko, Naoto Hoshi
doaj +1 more source
Presynaptic calcium channels [PDF]
Neuroscience Research, 2018 Presynaptic Ca2+ entry occurs through voltage-gated Ca2+ (CaV) channels which are activated by membrane depolarization. Depolarization accompanies neuronal firing and elevation of Ca2+ triggers neurotransmitter release from synaptic vesicles. For synchronization of efficient neurotransmitter release, synaptic vesicles are targeted by presynaptic Ca2 ...
openaire +4 more sources
Calcium channels in lymphocytes [PDF]
Immunology, 2001 On B and T lymphocytes, ligation of the antigen receptor (AgR) induces a biphasic Ca2+ response. In the initial phase there is a large elevation in the intracellular Ca2+ concentration as a consequence of Ca2+ release from intracellular stores. This is followed by a lower, but prolonged elevation that is dependent on extracellular Ca2+.1,2 This simple ...
Leanne Thwaite, Gillian Grafton
openaire +3 more sources
Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity
Frontiers in Pharmacology, 2018 As an oxidative stress sensor, transient receptor potential melastatin 2 (TRPM2) channel is involved in many physiological and pathological processes including warmth sensing, ischemia injury, inflammatory diseases and diabetes.
Yuhuan Luo +4 more
doaj +1 more source
Calcium Channel Blocker Overdose Simulation
MedEdPORTAL, 2015 Introduction Accidental poisoning and drug overdose are a common occurrence in the emergency medicine setting. Often it is unknown what substances the patient has taken.
Michael Maniaci +2 more
doaj +1 more source