Results 21 to 30 of about 295,986 (313)
An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans. [PDF]
PLoS Genetics, 2010 The large conductance, voltage- and calcium-dependent potassium (BK) channel serves as a major negative feedback regulator of calcium-mediated physiological processes and has been implicated in muscle dysfunction and neurological disorders.
Linu S Abraham +4 more
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Activation of Calcium Channels
Biophysical Journal, 1984 Activation of Ca channels has been described as a Hodgkin-Huxley process in which the time constants have ratios of two or greater (1, 2, 3) or as a three-state linear sequential process with two very different time constants (4). We examined activation by measuring the turn-on and turn-off of macroscopic Ca currents and the discharge of single Ca ...
Arthur Brown +2 more
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Mitogens and Calcium Channels [PDF]
Physiology, 1997 Mitogens and, in particular, growth factors can induce changes in free intracellular Ca2+ concentration by opening voltage-independent cationic channels, with different degrees of Ca2+ selectivity. Recent work has provided preliminary insights into the nature of these channels and their role in the control of cell cycle progression.
LOVISOLO, Davide +3 more
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43. Calmodulin regulating calcium sensitivity of Na channels
Journal of the Saudi Heart Association, 2016 By extrapolating information from existing research and observing previous assumptions regarding the structure of the Na Channel, this experiment was conducted under the hypothesis that the Na Channel is in part regulated by the calmodulin protein, as a ...
R. Vegiraju
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Medicine, 2003 Overdose of calcium channel blockers is potentially lethal. Verapamil and diltiazem are much more dangerous than dihydropyridines. Hypotension with (verapamil and diltiazem) or without (dihydropyridines) heart block and bradycardia are the most important features.
Ian M Whyte +5 more
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Physiology, 2017 In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on ...
James W. Putney, Mohamed Trebak
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Cell Reports, 2012 Although calcium influx triggers endocytosis at many synapses and non-neuronal secretory cells, the identity of the calcium channel is unclear. The plasma membrane voltage-dependent calcium channel (VDCC) is a candidate, and it was recently proposed that
Lei Xue +7 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 2000 We propose a model of calcium channels that can explain most of their observed properties, including the anomalous mole fraction effect and mutation of the glutamate residues. The structure grossly resembles that of the KcsA potassium channel except for the presence of an extracellular vestibule and a shorter selectivity filter containing four ...
Corry, Ben +3 more
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Calcium channels for endocytosis [PDF]
The Journal of Physiology, 2014 Exocytosis and endocytosis need to be tightly balanced to keep cell surface area constant. This is of particular relevance for presynaptic terminals, where endocytosis needs to compensate for the ongoing exocytosis of synaptic vesicle to ultimately guarantee reliable synaptic transmission.
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Cortisol modulates calcium release-activated calcium channel gating in fish hepatocytes
Scientific Reports, 2021 Glucocorticoids (GCs) are rapidly released in response to stress and play an important role in the physiological adjustments to re-establish homeostasis.
Chinmayee Das +3 more
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