Results 1 to 10 of about 6,896 (176)

Applied Research on Innovation and Development of Blue Calico of Chinese Intangible Cultural Heritage Based on Artificial Intelligence [PDF]

open access: yesScientific Reports
In light of the challenges currently facing the inheritance of blue calico, including the reduction in the number of inheritors and the contraction of the market, this paper puts forth a stylistic transfer method based on an enhanced cycle consistency ...
Jialiang He
exaly   +3 more sources

Longitudinal analysis of body weight reveals homeostatic and adaptive traits linked to lifespan in diversity outbred mice [PDF]

open access: yesNature Communications
Dense temporal measurements of physiological health, using simple and consistent assays, are essential to characterize biological processes associated with aging and evaluate the effectiveness of interventions on these processes.
G. V. Prateek   +6 more
doaj   +2 more sources

Automated cardiac MRI analysis for robust profiling of heart failure models in mice [PDF]

open access: yesScientific Reports
Heart failure with preserved ejection fraction (HFpEF) is a complex, age-related cardiovascular disease with limited treatment options, partly due to a poor understanding of underlying mechanisms, lack of robust preclinical models and diagnostic tools ...
Thulaciga Yoganathan   +7 more
doaj   +2 more sources

Classification and Recognition of the Nantong Blue Calico Pattern Based on Deep Learning

open access: yesJournal of Engineered Fibers and Fabrics
The Nantong blue calico pattern is a significant and indispensable part of China’s intangible cultural heritage, representing an artistic form of weaving and dyeing.
Ke-Ke Sun
exaly   +2 more sources

Parameter-efficient fine-tuning enables scalable transfer of regulatory sequence models to novel contexts [PDF]

open access: yesGenome Biology
Background DNA sequence deep learning models can accurately predict epigenetic and transcriptional profiles, enabling analysis of gene regulation and genetic variant effects. While large-scale models like Enformer and Borzoi are trained on abundant data,
Han Yuan   +2 more
doaj   +2 more sources

Exploring a crossroads in the aging process [PDF]

open access: yeseLife
Experiments on yeast show that the nuclear pore complex has a central role in the loss of chromosomes associated with aging.
Kiyan Shabestary, Daniel E Gottschling
doaj   +2 more sources

Systematic metabolite screening identifies functional regulators of the adenosine A2A receptor [PDF]

open access: yesCommunications Chemistry
The adenosine A2A receptor (A2AR) is a Class A G protein-coupled receptor (GPCR) that regulates inflammation, glucose metabolism, and energy homeostasis in metabolically active tissues. While the effects of small-molecule ligands and protein interactions
Prashant Rao   +11 more
doaj   +2 more sources

Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition

open access: yesCommunications Chemistry, 2023
Pregnancy-Associated Plasma Protein A isoforms, PAPP-A and PAPP-A2, are metalloproteases that cleave insulin-like growth factor binding proteins (IGFBPs) to modulate insulin-like growth factor signaling.
Janani Sridar   +11 more
doaj   +1 more source

3D mouse pose from single-view video and a new dataset

open access: yesScientific Reports, 2023
We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers ...
Bo Hu   +18 more
doaj   +1 more source

Novel insights from a multiomics dissection of the Hayflick limit

open access: yeseLife, 2022
The process wherein dividing cells exhaust proliferative capacity and enter into replicative senescence has become a prominent model for cellular aging in vitro.
Michelle Chan   +19 more
doaj   +1 more source

Home - About - Disclaimer - Privacy