Results 31 to 40 of about 6,896 (176)

Grassy Mountain Mine project alternatives assessment report

open access: yes, 2021
submitted to: Department of Geology and Mineral Industries ; prepared by: Calico Resources USA Corp.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

XChrom: A Cross‐Cell Chromatin Accessibility Prediction Model Integrating Genomic Sequence and Cellular Context

open access: yesAdvanced Science, EarlyView.
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao   +5 more
wiley   +1 more source

Prediction of First and Recurrent Falls in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective To develop and externally validate prediction models for next‐year falls in Parkinson's disease (PD), and to evaluate the incremental value of imaging and fluid biomarkers. Methods We developed models in Parkinson's Progression Markers Initiative (PPMI) to predict next‐year falls with external validation in University of Pennsylvania (UPenn ...
Joaquin A. Vizcarra   +13 more
wiley   +1 more source

The Moral Economy of the 1719-20 Calico Riots [PDF]

open access: yes, 2015
This thesis examines narratives created by middle rank writers during the English Calico riots of 1719-1720 and contrasts these legitimizing notions with those investigated by E. P.
Harris, Mark C
core   +1 more source

A genome‐scale yeast library with inducible expression of individual genes

open access: yesMolecular Systems Biology, 2021
The ability to switch a gene from off to on and monitor dynamic changes provides a powerful approach for probing gene function and elucidating causal regulatory relationships.
Yuko Arita   +14 more
doaj   +1 more source

Transition Metal Compounds as Thermochromic Materials: Classification, Properties, Limitations, and Applications

open access: yesEcoEnergy, EarlyView.
This review systematically examines how different transition metal compounds—such as binary and multinary metal oxides, halides, sulfides, and salts—exhibit thermochromism based on the d‐electron configurations of their transition metal cations. It focuses on three main mechanisms of thermochromism: phase transition, charge transfer, and bandgap change.
Jie Wang   +5 more
wiley   +1 more source

BiDAC-dependent degradation of plasma membrane proteins by the endolysosomal system

open access: yesNature Communications
The discovery of bifunctional degradation activating compounds (BiDACs) has led to the development of a new class of drugs that promote the clearance of their protein targets.
Sammy Villa   +12 more
doaj   +1 more source

Disease‐Duration–Specific Percentiles for Prospective Subtyping of Parkinson's Disease: A PPMI‐Based Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida   +4 more
wiley   +1 more source

Underwear: Calico Knickers

open access: yes, 2022
Sister Clare Veronica Wyman writes that sisters wore calico knickers under their skirts. Before these calico knickers it would have been \u27drawers\u27 — they were like two separate legs joined at the front and open at the back, held in place by ...
Wyman, Clare Veronica
core   +1 more source

Characterizing aging-related genetic and physiological determinants of spinal curvature

open access: yesCommunications Medicine
Background: Increased spinal curvature is one of the most recognizable aging traits in the human population. However, despite high prevalence, the etiology of this condition remains poorly understood. Methods To gain better insight into the physiological,
Frances M. Wang   +5 more
doaj   +1 more source

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